Results 151 to 160 of about 126,252 (290)

Recycling the LDL receptor to combat atherosclerosis

Aging, 2018
Jan Albert Kuivenhoven, Bart van de Sluis, Dyonne Y. Vos   +2 more
openaire   +4 more sources

Exploring heart failure prevalence and dimensions: A comprehensive NT‐proBNP study in high‐risk primary care patients

ESC Heart Failure, EarlyView.
The diagnostic pathway of high‐risk primary care patients through NT‐proBNP. Abstract Introduction Early detection of heart failure (HF), particularly in asymptomatic individuals, is essential for timely intervention. This study aimed to determine the prevalence of HF among high‐risk individuals in primary care using N‐terminal probrain natriuretic ...
Ahmet Celik, Emrah Yesil, Unal Kılıç, Gizem Akcay Ozyurt, Selman Aytimur, Mustafa Demir, Huseyin Naci Eker, Ayse Siddika Col, Cemil Ilker Altiparmak, Mustafa Ergen, Selen Bozkaya, Ismail Sefa Okyay, Ibrahim Ethem Kerem, Kiristin Marina Arap, Melike Yirtar, Deniz Korkmaz, Ali Kırdağ, Ismail Turkay Ozcan   +17 more
wiley   +1 more source

Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial

ESC Heart Failure, EarlyView.
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang, Rui Fan, Shaozhao Zhang, Junlin Zhong, Yiquan Huang, Peihan Xie, Shanshan Yin, Xiaomin Ye, Xinghao Xu, Rihua Huang, Zhenyu Xiong, Yue Guo, Menghui Liu, Yifen Lin, Suhua Li, Xiaoxian Qian, Jinlai Liu, Xiaodong Zhuang, Xinxue Liao   +18 more
wiley   +1 more source

New lipid therapies: PCSK9 inhibitors

Journal of Clinical and Translational Endocrinology Case Reports, 2016
Pharmacologic therapy reduces cardiovascular risk in a variety of primary and secondary prevention clinical situations in addition to lifestyle modifications. Low density lipoprotein cholesterol (LDL-C) is a key mediator of atherogenesis.
Farah Meah, DO, Arshi Basit, MD, Alaleh Mazhari, DO, Mary Ann Emanuele, MD, Nicholas Emanuele, MD   +4 more
doaj  

Prognostic value of lipid parameters among patients with heart failure: A systematic review and meta‐analysis

ESC Heart Failure, EarlyView.
Abstract Aims We sought to evaluate the prognostic value of different lipid parameters in patients with heart failure (HF). Methods and Results Electronic databases including MEDLINE, Embase, CENTRAL, and Web of Science were searched to identify studies that reported the association of any of the four lipid parameters [total cholesterol (TC), high ...
Ahmed Sayed, Hesham Afify, Malak Munir, Ibrahim ElGarhy, Omar Shazly, Mohamed ElRefaei, Saeed Ahmed, Ahmed Mazen Amin, Omar Chikh Amine, Islam Y. Elgendy   +9 more
wiley   +1 more source

LDL receptor traffic: in the fast lane [PDF]

European Heart Journal, 2019
Graciela E. Delgado, Winfried März, Winfried März, Winfried März, Marcus E. Kleber   +4 more
openaire   +2 more sources

The effects of early exercise on cardiovascular biomarkers in patients with congestive heart failure

ESC Heart Failure, EarlyView.
Abstract Background Exercise training improves functional outcomes in chronic heart failure (HF), but the effects of early in‐hospital physical activity on cardiovascular biomarkers and prognosis in acute congestive heart failure (AHF) patients remain unclear.
Yanxiang Sun, Xuansheng Huang, Bing Hu, Zidi Wu, Yanchun Zhang, Yong Yuan, Li Feng   +6 more
wiley   +1 more source

Orticumab: the potential to harness oxidized LDL to reduce coronary inflammation with plaque-targeted therapy. [PDF]

Curr Opin Lipidol
Farina CJ, Lu W, Nilsson J.
europepmc   +1 more source

Novel three‐dimensional ECG algorithm for reliable screening for cardiac amyloidosis

ESC Heart Failure, EarlyView.
The present manuscript describes the derivation and validation of an algorithm for screening of cardiac amyloidosis using 3‐dimensional ECG. The algorithm is based on a ECG vector loop, acquired over the duration of 15 seconds using 4 electrodes. With this easy to perform method, we describe a high diagnostic accuracy for the detection of cardiac ...
Amir A. Mahabadi, Jan Knobeloch, Viktoria Backmann, Lars Michel, Markus S. Anker, Reza Wakili, Christian Fach, Stefan D. Anker, Tienush Rassaf   +8 more
wiley   +1 more source

Low LDL-Cholesterol and Hemorrhagic Risk: Mechanistic Insights and Clinical Perspectives. [PDF]

Int J Mol Sci
Siniscalchi C, Basaglia M, Meschi T, Imbalzano E, Futura Bernardi F, Perrella A, Trama U, Passannanti A, Di Micco P, Schiano C.   +9 more
europepmc   +1 more source