Results 161 to 170 of about 77,479 (303)

Berberine alleviates pyroptosis of retinal ganglion cells in diabetic retinopathy by regulating AKT1, JUN, and STAT3

open access: yesIbrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li   +7 more
wiley   +1 more source

Novel Bioactive alkaloids from Nepalese Corydalis chaerophylla D.C. acting on the regulation of PCSK9 and LDL-R in vitro

open access: yes
reservedL'aterosclerosi è una patologia cronica infiammatoria che colpisce le arterie di medio-grande calibro. È caratterizzata dall'accumulo di lipidi, cellule infiammatorie e componenti fibrotici nella parete arteriosa, che porta alla formazione di ...
BENETAZZO, VERONICA
core  

Synthesized flavone attenuates diabetes‐induced neurodegeneration through regulation of oxidative stress and metabolic‐neurodegenerative molecular pathways

open access: yesIbrain, EarlyView.
Neuroprotective efficacy of flavone (2‐phenyl‐4H‐chromen‐4‐one). The study aimed to explore the potential of a synthetic derivative (flavone) of a phytocompound, which is involved in neuroprotection activities. Experimental strategies included the characteristics of compound, in‐silico analysis, and in vivo assessments.
Karishma Sen   +9 more
wiley   +1 more source

Genetic variation at the apolipoprotein B gene and associations with coronary heart disease and its factors.

open access: yes, 1996
PhDCoronary heart disease (CED) is the major cause of mortality in Western societies. The main risk factors are plasma lipoprotein concentrations, smoking, blood pressure and family history.
Rajput-Williams, Jayshri
core  

Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li   +10 more
wiley   +1 more source

Low-density lipoproteins in human serum competitively inhibit the binding and entry of vesicular stomatitis virus. [PDF]

open access: yesMol Ther Adv
Vandergaast R   +6 more
europepmc   +1 more source

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