Results 181 to 190 of about 73,504 (258)

Targeting Atherosclerosis: Cholesterol-Lowering Therapies with a New Immunometabolic Dress for an Old Disease. [PDF]

J Clin Med
Julve J, Rodriguez-Calvo R, Perret B, Martinez LO, Mauricio D.   +4 more
europepmc   +1 more source

Beyond BMI: The Impact of the New Lancet Commission Diagnostic Criteria on Prevalence of Obesity in the United States

Obesity, EarlyView.
ABSTRACT Objective This study compared population characteristics and overall US prevalence of obesity over time using the BMI criteria and the 2025 Lancet Commission criteria (i.e., the Excess Adiposity criteria). Methods We analyzed data from 58,053 adults aged ≥ 20 years in the National Health and Nutrition Examination Survey from 1999 to 2023.
Jennifer H. Hwang, Neda Laiteerapong
wiley   +1 more source

Recent Advances in Nanodelivery Systems Based on Extracellular and Intracellular Reprogramming Strategies for Enhanced Therapy of Atherosclerosis. [PDF]

Int J Nanomedicine
Liu Y, Li Y, Wang Q, Wu M, Zhang Z, Liang X, Yang X, He X, Tang J, Li C, Yuan P, Li T.   +11 more
europepmc   +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models

Obesity, EarlyView.
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand, Camille Le Cudennec, Estelle Grasset, Natalia Breyner, Claire Bigot, Pierre Dillard, Thierry Sulpice   +6 more
wiley   +1 more source

LDL atherogenicity determined by size, density, oxidation, apolipoprotein(a), and electronegativity: an updated review. [PDF]

Front Cardiovasc Med
Akyol O, Chiang HH, Burns AR, Yang CY, Woodside DG, Sawamura T, Sánchez-Quesada JL, Gotto AM, Chen CH.   +8 more
europepmc   +1 more source

Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency

Obesity, EarlyView.
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak, Arshdeep Rattol, Eduardo Grunvald   +2 more
wiley   +1 more source

A Position Paper on Lipoprotein(a) From the Lipoprotein(a) Task Force of the Korean Society of Lipid and Atherosclerosis: Current Evidence, Clinical Applications, and Future Directions. [PDF]

Korean Circ J
Jang Y, Lee JH, Lee SG, Choe HJ, Park SM, Jeong IK, Kim BJ, Lipoprotein(a) Task Force of the Korea Society of Lipid and Atherosclerosis.   +7 more
europepmc   +1 more source

The Plasma Free Fatty Acid Carrier Proteome is Altered in Diet‐Induced and Genetically Obese Mice

Obesity, EarlyView.
ABSTRACT Objective We aimed to examine the effect of obesity on the plasma free fatty acid (FFA) carrier proteome in mice. Methods From 6 to 20 weeks of age, male and female C57BL/6J wild‐type mice were fed either a low‐fat diet (10% of kilocalories from fat) or a high‐fat diet (60% of kilocalories from fat), and leptin‐deficient ob/ob mice were fed a ...
Keigo Tomoo, Yi Zhang, Ariana Zoe Diaz Portalatin, Gregory C. Henderson   +3 more
wiley   +1 more source

Molecular Mechanisms Underlying Atherosclerosis and Current Advances in Targeted Therapeutics. [PDF]

Int J Mol Sci
Zhu B.
europepmc   +1 more source

Outcomes of Direct Vocal Fold Testosterone Injections in Hormone‐Naïve Adults: A Case Series

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Two nonbinary testosterone‐naïve individuals were seen at the Northwestern Memorial Hospital Voice Clinic. The objective was to determine the effectiveness of direct testosterone injections to the vocal folds for voice masculinization in testosterone‐naïve individuals.
Mariah E. Morton‐Jones, Zhe‐chen Guo, Jaymie Bromfield, Kristen Lee, Jonelyn Langenstein, Andrew P. Stein   +5 more
wiley   +1 more source