Results 201 to 210 of about 73,504 (258)

Oxidized LDL receptors: a recent update

Current Opinion in Lipidology, 2023
Purpose of review LDL in its oxidized form, or ‘oxLDL’, is now generally acknowledged to be highly proatherogenic and to play a significant role in atherosclerotic plaque formation. Therefore, there has been increasing interest in understanding the significance of oxLDL and its receptors in different phases of atherosclerosis ...
Mohd Azeem, Khan, Irshad, Mohammad, Sohom, Banerjee, Akanksha, Tomar, Kottayil I, Varughese, Jawahar L, Mehta, Anmol, Chandele, Arulandu, Arockiasamy   +7 more
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LDL receptor polymorphisms revisited

Blood, 2010
In this issue of Blood , Martinelli and colleagues describe that certain single-nucleotide polymorphisms in the LDL receptor gene independently associate with high plasma levels of coagulation factor VIII in patients with coronary artery disease.[1][1] In 1985, Drs M. S. Brown and J.
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LDL Receptor's β-Propeller Displaces LDL

Science, 2002
The low density lipoprotein receptor (LDLR) binds to lipoprotein extracellularly and releases it in the endosome. In his Perspective, Innerarity discusses new structural work (Rudenkoet al.) that shows that an interdomain interaction that occurs at low pH likely displaces ligand from the receptor in the endosome.
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[LDL receptors].

Revue medicale de Bruxelles, 1991
The low density lipoprotein receptor removes the cholesterol-carrying lipoproteins from blood. When the activity of LDL receptors is reduced, as a result of genetic or acquired abnormalities, LDL increases in blood, resulting in atherosclerosis. Heterozygote familial hypercholesterolemia (one mutant gene) is characterized by a 50% reduction of LDL ...
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LDL-receptor

2000
Opisan je značaj LDL-receptora u metabolizmu kolesterola te metoda protočne citometrije s pomoću koje se može dobiti uvid u relativnu aktivnost LDL-receptora na površini kultiviranih monocita.
Užarević, Branka, Zrinski Topić, Renata   +1 more
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LDL Receptor‐Related Proteins in Neurodevelopment

Traffic, 2003
Low‐density lipoprotein receptor‐related proteins (LRPs) are evolutionarily ancient cell‐surface receptors with diverse biological functions. All are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment.
Petra, May, Joachim, Herz
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Scavenger Receptors, Oxidized LDL, and Atherosclerosis

Annals of the New York Academy of Sciences, 2001
Abstract: Oxidized LDL (OxLDL) competes with oxidatively damaged and apoptotic cells for binding to mouse peritoneal macrophages, implying the presence of one or more common domains. However, the nature of the ligands involved has not been determined.
A, Boullier, D A, Bird, M K, Chang, E A, Dennis, P, Friedman, K, Gillotre-Taylor, S, Hörkkö, W, Palinski, O, Quehenberger, P, Shaw, D, Steinberg, V, Terpstra, J L, Witztum   +12 more
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LOWERING PLASMA CHOLESTEROL BY RAISING LDL RECEPTORS

Atherosclerosis Supplements, 1981
More than 93 per cent of the body's cholesterol is located in cells, where it performs vital structural and metabolic functions; only about 7 per cent circulates in plasma, where it predisposes to ...
M S, Brown, J L, Goldstein
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Determination of LDL Receptors on Cultured Lymphocytes Using Fluorescein-Labeled LDL

American Journal of Clinical Pathology, 1982
A rapid, sensitive procedure for the detection of LDL receptors on cell surface without using radioisotopes is described. Fluorescein-isothiocyanate (FITC) labeled LDL bound with cultured human lymphocytes, and the degree of that binding was compatible with that of 125 I-labeled LDL.
H, Sakai, H, Kaneshige, M, Endoh
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