Results 141 to 150 of about 2,401,298 (264)

Human mast cells express leptin and leptin receptors

Histochemistry and Cell Biology, 2009
J. Taildeman, C. Pérez-Novo, I. Rottiers, L. Ferdinande, A. Waeytens, Veerle De Colvenaer, C. Bachert, P. Demetter, W. Waelput, K. Braet, C. Cuvelier   +10 more
semanticscholar   +1 more source

Precision nutrition in weight loss and neuroendocrine control of people with obesity: The study protocol of a factorial randomised controlled trial (GenON Programme)

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Precision nutrition, guided by genetic testing, has emerged as a promising approach for managing obesity. However, robust clinical trials testing its effectiveness in real‐world dietary interventions remain scarce. The GenOn Programme aims to evaluate whether tailoring nutritional care based on genetic risk for obesity enhances weight ...
Karla P. Balbino, Ana Claudia P. Kravchychyn, Flávia G. Cândido, Mariana de Moura e Dias, Tiago Antônio de O. Mendes, Leandro Licursi de Oliveira, Luiza Carla V. Castro, Josefina Bressan, Ana Laura de la Garza, Fermín I. Milagro, María A. Zulet, Helen Hermana M. Hermsdorff   +11 more
wiley   +1 more source

Is AMP‐activated protein kinase activation a central mechanism of cardio‐metabolic outcomes after metabolic and bariatric surgery?

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity. It usually results in spectacular weight loss, associated with improvements of obesity‐associated comorbidities. The mechanisms underlying these benefits are not fully understood but could involve a postoperative activation of the enzyme 5′ AMP‐activated ...
Adrien Delcour, Nathalie Niederhoffer
wiley   +1 more source

Mechanism of LEPR-mediated cholesterol metabolism involved in NK cell function suppression under simulated microgravity. [PDF]

NPJ Microgravity
Lv H, Yang H, Guo X, Li J, Xie Y, Jiang C, Shi J, Huang Q, Shao D.   +8 more
europepmc   +1 more source

Melanocortin receptors in leptin effects

Nature, 1997
R. Seeley, K. Yagaloff, Stewart L. Fisher, P. Burn, T. E. Thiele, G. Dijk, D. Baskin, M. Schwartz   +7 more
semanticscholar   +1 more source

Artificial lipidation of proteins and peptides: from mechanism to clinical applications

The FEBS Journal, EarlyView.
Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley   +1 more source

The effect of alpha lipoic acid and caffeine loaded into chitosan nanoparticles on the hypothalamic amino acid neurotransmitters in a rat model of obesity. [PDF]

Sci Rep
Khadrawy YA, Khoder NM, El-Gizawy MM, Hosny EN, Sawie HG, Elkholy NS, Amer HM, Ezz HSA.   +7 more
europepmc   +1 more source

Leptin signalling pathways in hypothalamic neurons

Cellular and Molecular Life Sciences, 2016
Obin Kwon, Ki Woo Kim, Min-Seon Kim
semanticscholar   +1 more source

The Effect of Diabetes on Outcomes of Non‐Surgical Periodontal Therapy: A Systematic Review With a Meta‐Analysis and Trial Sequential Analysis

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective The aim of this systematic review was to critically assess and synthesise the current scientific evidence of the potential impact of diabetes mellitus (DM) on treatment outcomes in periodontitis patients following NSPT, incorporating recent advancements in meta‐analytical techniques.
L. P. M. Weijdijk, T. M. J. A. Thomassen, N. C. de Keyzer, E. E. J. Mayer, C. Valkenburg, G. A. van der Weijden, D. E. Slot   +6 more
wiley   +1 more source

Central leptin pathways in metabolic homeostasis. [PDF]

Clin Sci (Lond)
Zhao Y, Laule C, Rahmouni K.
europepmc   +1 more source