Results 141 to 150 of about 783,628 (249)

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

"RAL" the LDLR to lysosomes for degradation. [PDF]

Life Metab
Guan Y, Huang Y, Li Z, Wang Y.
europepmc   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Could chimeric antigen receptor-T cell treatment of atherosclerosis in mice translate to a human therapy? [PDF]

Ann Transl Med
Gieseg S, Hock B, Ogugofor M, McCormick S.   +3 more
europepmc   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

How lipid ingestion is sensed: the mechanisms underlying intestinal hormone secretion. [PDF]

Clin Sci (Lond)
Santos-Hernández M, Gribble FM, Reimann F.   +2 more
europepmc   +1 more source

When Literature Priors Are Removed: Clinical Rank Shifts and Transancestral Stability in Antipsychotic Low-Density Lipoprotein (LDL)-Risk Modelling. [PDF]

Cureus
Cheung N, Cheung HK, Yu YW, Tsang YY.
europepmc   +1 more source

The Scavenger Function of LSECs, a Regulator of Liver Diseases. [PDF]

Curr Issues Mol Biol
Zhou J, Zhang L, Wang J, Zhang C, Tian C.   +4 more
europepmc   +1 more source

Lysophosphatidylcholine and lysophosphatidic acid as key messengers in atherosclerosis: from a lipid-inflammation vicious cycle to therapeutic translation. [PDF]

Front Cardiovasc Med
Guan X, Li Z, Cheng H, Li J, Wen N, Wang L.   +5 more
europepmc   +1 more source

Stabilization of PUFA‐Rich Mayonnaise Against Lipid Oxidation: A Review of the Last Three Decades of Research

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Mayonnaise, a widely consumed oil‐in‐water emulsion, is highly susceptible to lipid oxidation due to its high content of polyunsaturated fatty acids (PUFAs) and the presence of pro‐oxidant factors such as low pH and iron from egg yolk. Over the past three decades, extensive research has focused on understanding oxidation mechanisms, analytical
Sakhi Ghelichi, Betül Yesiltas, Charlotte Jacobsen   +2 more
wiley   +1 more source