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ESC Heart Failure, EarlyView.Abstract Aims There are limited tools to predict long‐term mortality among patients hospitalized with acute heart failure (AHF) in China. This study aimed to develop and validate a model to predict long‐term mortality risk among patients who were hospitalized with AHF and discharged alive.
Wei Wang +8 more
wiley +1 more source
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Lipoprotein Receptors in the Nervous System
Annual Review of Biochemistry, 2002▪ Abstract The low-density–lipoprotein (LDL) receptor family is an evolutionarily ancient gene family of structurally closely related cell-surface receptors. Members of the family are involved in the cellular uptake of extracellular ligands and regulate diverse biological processes including lipid and vitamin metabolism and cell-surface protease ...
Joachim Herz, Hans H. Bock
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Lipoprotein receptors and cholesterol homeostasis
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1983Thomas L. Innerarity, Robert W. Mahley
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Lipoprotein receptors and atherosclerosis
Clinical Science, 1986Mammalian cholesterol metabolism is governed by two key features of the steroid nucleus: it is poorly soluble in plasma and it cannot be degraded in animal tissues. Cells which require the lipid import it through their cytoplasmic membranes in the form of solubilized lipid-protein complexes, and a similar export mechanism is essential in order to ...
Christopher J. Packard, James Shepherd
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Macrophage lipoprotein receptors
Journal of Cell Science, 1988ABSTRACT Macrophages possess a number of surface receptors that are capable of mediating the internalization of lipoproteins. The low-density lipoprotein (LDL) receptor of human monocyte macrophages recognizes apolipoprotein B-100 and apolipoprotein E and is rapidly regulated in response to changes in intracellular cholesterol levels. In
Margaret E. Haberland +4 more
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Regulation of plasma cholesterol by lipoprotein receptors.
Science, 1981The lipoprotein transport system holds the key to understanding the mechanisms by which genes, diet, and hormones interact to regulate the plasma cholesterol level in man.
Michael S. Brown +2 more
semanticscholar +1 more source
Annual Review of Biochemistry, 1983
PERSPECTIVES AND SUMMARY ............................... .... ....................................... 224 UPTAKE OF LIPOPROTEIN-BOUND CHOLESTEROL BY MACROPHAGES ..............................................................................................
M. Brown, J. Goldstein
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PERSPECTIVES AND SUMMARY ............................... .... ....................................... 224 UPTAKE OF LIPOPROTEIN-BOUND CHOLESTEROL BY MACROPHAGES ..............................................................................................
M. Brown, J. Goldstein
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Hepatocytic lipoprotein receptors and intracellular lipoprotein catabolism
Hepatology, 1988Hepatocytes, as the major site of synthesis and terminal catabolism of plasma lipoproteins, exert the major regulatory influence on the concentration of atherogenic lipoproteins in blood plasma and may thereby influence the rate of atherogenesis. The LDL receptor on the microvillous sinusoidal surface of hepatocytes mediates the catabolism of remnants ...
J M D Richard Havel, Robert L. Hamilton
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Lipoprotein-receptor interactions
1986Publisher Summary This chapter focuses on the lipoprotein–receptor interactions. Lipoprotein receptors function as a major control mechanism for the regulation of lipoprotein catabolism. The classical studies of Goldstein and Brown demonstrated the importance of low-density lipoprotein (LDL) receptors in supplying cells with cholesterol and in ...
Robert W. Mahley +2 more
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