Results 201 to 210 of about 127,504 (263)

Macrophage lipoprotein receptors

Journal of Cell Science, 1988
ABSTRACT Macrophages possess a number of surface receptors that are capable of mediating the internalization of lipoproteins. The low-density lipoprotein (LDL) receptor of human monocyte macrophages recognizes apolipoprotein B-100 and apolipoprotein E and is rapidly regulated in response to changes in intracellular cholesterol levels. In
A M, Fogelman, B J, Van Lenten, C, Warden, M E, Haberland, P A, Edwards   +4 more
openaire   +2 more sources

Lipoprotein receptors and atherosclerosis

Clinical Science, 1986
Mammalian cholesterol metabolism is governed by two key features of the steroid nucleus: it is poorly soluble in plasma and it cannot be degraded in animal tissues. Cells which require the lipid import it through their cytoplasmic membranes in the form of solubilized lipid-protein complexes, and a similar export mechanism is essential in order to ...
J, Shepherd, C J, Packard
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Lipoprotein Receptors

Cellular and molecular biology (Noisy-le-Grand, France), 1994
Lipoprotein receptors are membrane proteins which play a central role in lipid metabolism. Although cells are capable of synthetizing de novo cholesterol from acetate, cholesterol is mostly of food origin or synthetized by the liver. The liver is the only organ which can catabolize the cholesterol and clear it from the circulation into biliary acids ...
W. J. S. de Villiers, G. A. Coetzee, D. R. van der Westhuyzen   +2 more
openaire   +3 more sources

Lipoprotein-receptor interactions

1986
Publisher Summary This chapter focuses on the lipoprotein–receptor interactions. Lipoprotein receptors function as a major control mechanism for the regulation of lipoprotein catabolism. The classical studies of Goldstein and Brown demonstrated the importance of low-density lipoprotein (LDL) receptors in supplying cells with cholesterol and in ...
T L, Innerarity, R E, Pitas, R W, Mahley
openaire   +2 more sources