Results 221 to 230 of about 127,504 (263)
Some of the next articles are maybe not open access.
The low density lipoprotein receptor
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989The study of familial hypercholesterolemia at the molecular level has led to its advancement from a clinical syndrome to a fascinating experimental system. FH was first described 50 years ago by Carl Müller who concluded that the disease produces high plasma cholesterol levels and myocardial infarctions in young people, and is transmitted as an ...
openaire +2 more sources
Receptor Interactions Controlling Lipoprotein Metabolism
Canadian Journal of Biochemistry and Cell Biology, 1984Lipoprotein receptors play a central role in lipoprotein metabolism and a major role in cholesterol homeostasis. The most completely characterized lipoprotein receptor is the LDL (low density lipoprotein) or apo-B,E(LDL) receptor. The apo-B,E(LDL) receptor is present on both hepatic and extrahepatic cells and is responsible for the metabolism of a ...
K H, Weisgraber +3 more
openaire +2 more sources
Lipoprotein receptors in oocyte growth
The Clinical Investigator, 1992The transport and removal of lipoproteins from the blood in the laying hen is of particular interest because it is a system in which the massive transport of lipid to one organ (the ovary) coexists with regulatory mechanisms for the control of lipid homeostasis in extraovarian tissues.
openaire +2 more sources
Hypertriglyceridemia: Lipoprotein Receptors and Atherosclerosis
1985We have shown first, that apoB mediates the binding of small VLDL Sf 20-60 and IDL, as well as LDL, to the LDL receptor. Second, apoE of an appropriate, accessible conformation is required for the binding of large VLDL to the LDL receptor; HTG-VLDL Sf greater than 60 but not normal VLDL Sf greater than 60 have this apoE population.
S H, Gianturco, A M, Gotto, W A, Bradley
openaire +2 more sources
Lipoprotein receptors in perspective
Current Opinion in Lipidology, 1992Recent findings regarding mutant founder genes, structure/function relationships and regulation of the LDL receptor are reviewed. New aspects regarding the control of the LDL receptor-related protein are presented. The structure and function of the scavenger receptor and the physiological role of the HDL receptor are considered.
Gerhard A. Coetzee +1 more
openaire +1 more source
Receptors for triglyceride-rich lipoproteins and their role in lipoprotein metabolism
Current Opinion in Lipidology, 1995The triglyceride-rich lipoproteins in normal human plasma are VLDL and chylomicrons and their remnants. Several receptors for these lipoproteins have been described, most of them belonging to the LDL receptor family. The LDL receptor itself is able to recognize remnants through apolipoprotein E.
openaire +2 more sources
Plasma lipoproteins and their receptors
Current Opinion in Structural Biology, 1991Apolipoproteins B and E play essential roles in the transport and endocytosis of the lipoprotein particles on which they reside. The appearance of a high-resolution structure for the receptor ligand domain of apolipoprotein E affords an opportunity to understand in detail its interaction with receptors.
openaire +1 more source
Lipoprotein - receptor interactions
1992Abstract The interaction of lipoproteins with their receptors is the first step of a homeostatic mechanism that controls plasma cholesterol levels, intracellular cholesterol metabolism, and lipoprotein catabolism. The classic studies of M. S. Brown and J. L. Goldstein (Univ.
Kay S Arnold +3 more
openaire +1 more source