Results 201 to 210 of about 2,543,592 (233)

Lipoprotein Receptors and Endothelial Cells

Seminars in Thrombosis and Hemostasis, 1988
The interaction of lipoproteins with endothelial receptors can result in alterations in macromolecular transport, in changes in monocyte adherence to the endothelium, and in the production of monocyte chemotactic factor by the endothelium. Monocyte migration in response to such factors can further alter lipoprotein transport into the subendothelial ...
A M Fogelman, Van Lenten Bj, Mary C. Territo, Berliner Ja, Mohamad Navab   +4 more
openaire   +3 more sources

Lipophorin receptor: The insect lipoprotein receptor

Resonance, 2013
The low-density lipoprotein receptor (LDLR), one of the best characterized cell-surface receptors, mediates cholesterol homeostasis and other functions in mammals. The members of the LDLR superfamily are structurally related and characterized by distinct functional domains.
G. Ravikumar, N. B. Vijayaprakash
openaire   +2 more sources

Lipoprotein receptors and atherogenic receptor-mediated mechanisms

Current Opinion in Lipidology, 1994
The liver plays a decisive role in the regulation of the plasma levels of atherogenic lipoproteins. The primary liver interaction site of chylomicron remnants and VLDL remnants (beta-VLDL) is still unidentified, whereas the subsequent cellular uptake is likely to be mediated in concert by the LDL receptor-related protein and the LDL receptor.
Martin K. Bijsterbosch, J. Kuiper, G. J. Ziere, T. J. C. Van Berkel   +3 more
openaire   +2 more sources

The low density lipoprotein receptor

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989
The study of familial hypercholesterolemia at the molecular level has led to its advancement from a clinical syndrome to a fascinating experimental system. FH was first described 50 years ago by Carl Müller who concluded that the disease produces high plasma cholesterol levels and myocardial infarctions in young people, and is transmitted as an ...
openaire   +3 more sources

Hypertriglyceridemia: Lipoprotein Receptors and Atherosclerosis

1985
We have shown first, that apoB mediates the binding of small VLDL Sf 20-60 and IDL, as well as LDL, to the LDL receptor. Second, apoE of an appropriate, accessible conformation is required for the binding of large VLDL to the LDL receptor; HTG-VLDL Sf greater than 60 but not normal VLDL Sf greater than 60 have this apoE population.
Sandra H. Gianturco, Antonio M. Gotto, William A. Bradley   +2 more
openaire   +3 more sources

Receptor Interactions Controlling Lipoprotein Metabolism

Canadian Journal of Biochemistry and Cell Biology, 1984
Lipoprotein receptors play a central role in lipoprotein metabolism and a major role in cholesterol homeostasis. The most completely characterized lipoprotein receptor is the LDL (low density lipoprotein) or apo-B,E(LDL) receptor. The apo-B,E(LDL) receptor is present on both hepatic and extrahepatic cells and is responsible for the metabolism of a ...
Karl H. Weisgraber, Thomas L. Innerarity, Stanley C. Rall, Robert W. Mahley   +3 more
openaire   +3 more sources

An extracellular beta-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components.

Journal of Molecular Biology, 1998
An abundant, widely dispersed, extracellular sequence repeat that contains a consensus YWTD motif is shown here to occur in groups of six contiguous repeats.
T. A. Springer
semanticscholar   +1 more source

Lipoprotein receptors in Alzheimer's disease

Trends in Neurosciences, 2006
Lipoprotein receptors have important roles in pathological processes that lead to Alzheimer's disease (AD). Previously, they were believed to act mainly by modulating the neuronal metabolism of cholesterol and apolipoprotein E, major risk factors for spontaneous AD.
Andersen, Olav Michael, Willnow, Thomas E.   +1 more
openaire   +4 more sources

Lipoprotein receptors in oocyte growth

The Clinical Investigator, 1992
The transport and removal of lipoproteins from the blood in the laying hen is of particular interest because it is a system in which the massive transport of lipid to one organ (the ovary) coexists with regulatory mechanisms for the control of lipid homeostasis in extraovarian tissues.
openaire   +2 more sources

Recognition of B2GPI by the Lipoprotein Receptors.

Blood, 2009
Abstract Abstract 851 Lipoprotein receptors of the LDLR family serve as clearance receptors for beta2-glycoprotein-I (B2GPI) and as signaling receptors for the B2GPI/antibody complexes in patients with antiphospholipid syndrome (APS).
Natalia Beglova, Changjin Lee, Alfredo De Biasio   +2 more
openaire   +2 more sources