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Sex and reproductive stage modify the effect of endogenous oestrogens on coronary atherosclerosis in rheumatoid arthritis. [PDF]
RMD OpenKarpouzas GA +6 more
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Targeting Atherosclerosis: Cholesterol-Lowering Therapies with a New Immunometabolic Dress for an Old Disease. [PDF]
J Clin MedJulve J +4 more
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The Role of Lipid Alteration in Multiple Sclerosis. [PDF]
Int J Mol SciDamiza-Detmer A +2 more
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Bile acid signaling mediates gut microbiota regulation of host lipid metabolism. [PDF]
Front MicrobiolLiu M +6 more
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Cellular and molecular biology (Noisy-le-Grand, France), 1994
Lipoprotein receptors are membrane proteins which play a central role in lipid metabolism. Although cells are capable of synthetizing de novo cholesterol from acetate, cholesterol is mostly of food origin or synthetized by the liver. The liver is the only organ which can catabolize the cholesterol and clear it from the circulation into biliary acids ...
W. J. S. de Villiers +2 more
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Lipoprotein receptors are membrane proteins which play a central role in lipid metabolism. Although cells are capable of synthetizing de novo cholesterol from acetate, cholesterol is mostly of food origin or synthetized by the liver. The liver is the only organ which can catabolize the cholesterol and clear it from the circulation into biliary acids ...
W. J. S. de Villiers +2 more
openaire +3 more sources
Macrophage lipoprotein receptors
Journal of Cell Science, 1988ABSTRACT Macrophages possess a number of surface receptors that are capable of mediating the internalization of lipoproteins. The low-density lipoprotein (LDL) receptor of human monocyte macrophages recognizes apolipoprotein B-100 and apolipoprotein E and is rapidly regulated in response to changes in intracellular cholesterol levels. In
A M, Fogelman +4 more
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Lipoprotein-receptor interactions
1986Publisher Summary This chapter focuses on the lipoprotein–receptor interactions. Lipoprotein receptors function as a major control mechanism for the regulation of lipoprotein catabolism. The classical studies of Goldstein and Brown demonstrated the importance of low-density lipoprotein (LDL) receptors in supplying cells with cholesterol and in ...
T L, Innerarity, R E, Pitas, R W, Mahley
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Lipoprotein receptors and atherosclerosis
Clinical Science, 1986Mammalian cholesterol metabolism is governed by two key features of the steroid nucleus: it is poorly soluble in plasma and it cannot be degraded in animal tissues. Cells which require the lipid import it through their cytoplasmic membranes in the form of solubilized lipid-protein complexes, and a similar export mechanism is essential in order to ...
J, Shepherd, C J, Packard
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Lipoprotein receptors: therapeutic implications
Journal of Hypertension, 1990Knowledge of the transport pathways for cholesterol in blood helps us to understand the mechanisms underlying genetic and acquired forms of hypercholesterolaemia, and sets the stage for rational treatment with diet and drugs. A key element is a cell-surface receptor that binds cholesterol-rich lipoproteins of intermediate and low density.
M S, Brown, J L, Goldstein
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