Results 31 to 40 of about 7,044 (182)

Lipoxin A4 Receptor Stimulation Attenuates Neuroinflammation in a Mouse Model of Intracerebral Hemorrhage [PDF]

open access: yesBrain Sciences, 2022
Intracerebral hemorrhage (ICH) is caused by the rupture of blood vessels in the brain. The excessive activation of glial cells and the infiltration of numerous inflammatory cells are observed during bleeding. Thrombin is a key molecule that triggers neuroinflammation in the ICH brain.
Risa Futokoro   +3 more
openaire   +3 more sources

Resolution of inflammation: an integrated view [PDF]

open access: yes, 2013
O.S. is supported by the NWO (VIDI project 91712303), theDFG (SO876/3-1, SO876/6-1, FOR809, SFB914 TPB08), theGerman-Israeli Foundation, and the Else Kro¨ner FreseniusStiftung. M.P.
Ortega-Gomez, A   +2 more
core   +3 more sources

Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

open access: yes, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz   +14 more
core   +1 more source

Arachidonic acid: Physiological roles and potential health benefits – A review

open access: yesJournal of Advanced Research, 2018
It is time to shift the arachidonic acid (ARA) paradigm from a harm-generating molecule to its status of polyunsaturated fatty acid essential for normal health.
Hatem Tallima, Rashika El Ridi
doaj   +1 more source

Targeting inflammation to reduce cardiovascular disease risk [PDF]

open access: yes, 2017
This joint themed section of the British Journal of Pharmacology and the British Journal of Clinical Pharmacology stems from a joint British Pharmacological Society – Italian Society of Pharmacology symposium held at the 37th National Congress of the ...
Cirino, Guiseppe, Maffia, Pasquale
core   +1 more source

Lipoxin A4 blocks embryo implantation by controlling estrogen receptor α activity [PDF]

open access: yesREPRODUCTION, 2013
Embryo implantation involves a complex regulatory network of steroid hormones, inflammatory cytokines, and immune cells. Lipoxin A4(LXA4), a biologically active eicosanoid with specific anti-inflammatory and pro-resolving properties, was recently found to be a novel modulator of estrogen receptor α (ERα).
Jing, Xiong   +7 more
openaire   +2 more sources

Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats

open access: yesFrontiers in Molecular Neuroscience, 2017
Antinociceptive pathways are activated in the periphery in inflammatory pain, for instance resolvins and opioid peptides. Resolvins are biosynthesized from omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid ...
Beatrice Oehler   +7 more
doaj   +1 more source

Formyl peptide receptor 1 suppresses gastric cancer angiogenesis and growth by exploiting inflammation resolution pathways

open access: yesOncoImmunology, 2017
Chronic inflammation can result from inadequate engagement of resolution mechanisms, mainly accomplished by specialized pro-resolving mediators (SPMs) arising from the metabolic activity of lipoxygenases (ALOX5/15) on ω-6 or ω-3 essential polyunsaturated
Nella Prevete   +6 more
doaj   +1 more source

Mechanisms of aspirin-sensitive asthma

open access: yesAllergology International, 2004
It is now widely accepted that aspirin, along with other non-steroidal anti-inflammatory drugs (NSAIDs), may precipitate asthma attacks in a minority of susceptible individuals.
Sun Ying   +2 more
doaj   +1 more source

Neuroprotection targeting protein misfolding on chronic cerebral hypoperfusion in the context of metabolic syndrome [PDF]

open access: yes, 2018
Metabolic syndrome (MetS) is a cluster of risk factors that lead to microvascular dysfunction and chronic cerebral hypoperfusion (CCH). Long-standing reduction in oxygen and energy supply leads to brain hypoxia and protein misfolding, thereby linking CCH
Capani, Francisco   +6 more
core   +1 more source

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