Results 61 to 70 of about 7,044 (182)

Identification, Cloning, and Functional Characterization of a Murine Lipoxin A4 Receptor Homologue Gene [PDF]

The Journal of Immunology, 2002
AbstractTo identify additional members of the murine N-formyl-Met-Leu-Phe peptide receptor family (fMLF-R), a mouse macrophage cDNA library was screened using the open reading frame of murine N-formyl peptide receptor. Four individual hybridizing cDNA clones were maintained through tertiary screening.
Michael W, Vaughn, Rita J, Proske, David L, Haviland   +2 more
openaire   +2 more sources

Lipoxin A4 analogue, BML-111, reduces platelet activation and protects from thrombosis

Thrombosis Journal
Formyl peptide receptors (FPRs) are members of seven transmembrane G protein-coupled receptors superfamily that exhibit different responses based on the nature of stimulating ligand type. FPRs have been shown to be present in platelets and regulate their
Shatha AlOmar, Joanne L Mitchell, Eman AlZahrani   +2 more
doaj   +1 more source

In regards to lipoxins as lipid mediators for the resolution of inflammation using the example of asthma

Acta Biomedica Scientifica
Asthma is the most important medical and social problem of our time due to its widespread prevalence, chronic course and heterogeneity, which determines the complexity of  treating this disease.
O. Yu. Kytikova, T. P. Novgorodtseva, I. S. Kovalenko   +2 more
doaj   +1 more source

Aspirin-Trigge red-Resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury [PDF]

, 2014
Acute Lung Injury (ALI) is a severe illness with excess mortality and no specific therapy. Protective actions were recently uncovered for docosahexaenoic acid -derived mediators, including D-series resolvins.
Carlo, T., Croze, RH., Eickmeier, O., Gao, F., Haworth, O., Hilberath, JN., Levy, BD., Pfeffer, MA., Seki, H., Uddin, M.   +9 more
core   +1 more source

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

Periodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis [PDF]

, 2017
National Institutes of Health grants GM-38765 and P50-DE016191 (C.N.S.), Welcome Trust Programme grant 086867/Z/08/Z (R.J.F. and M.P.) and Project grant 085903/Z/08 (R.J.F.) and Arthritis Research Campaign UK fellowships 18445 and 18103 (to L.V.N.
AR Rodriguez, BE Chatterjee, C Weber, Charles N. Serhan, CN Serhan, CN Serhan, CN Serhan, D Cooper, D Rittirsch, D Rittirsch, DG Souza, Dianne Cooper, DM Mosser, DW Gilroy, JA Buras, Lisa Summers, LR Farolan, Lucy V. Norling, M Bucci, MA Flierl, Matthew Spite, Mauro Perretti, MF Osuchowski, MJ Paul-Clark, Nicos A. Petasis, P Kubes, P Singer, R Haworth, Roderick J. Flower, Rong Yang, RS Hotchkiss, S Hong, S Moncada, SM Prescott, T Shimizu, T Shimizu, T Takano, TT Pluess, V Litvak, VY Dombrovskiy, X Huang   +40 more
core   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source

Antimicrobial peptides and eicosanoids : roles and interactions in inflammation and host defense [PDF]

, 2017
Antimicrobial peptides (AMPs) have a broad spectrum of activities and exert their functions by both direct killing of microbes through the interaction with the microbial membrane, and modulation of innate and adaptive immunity of the host.
Tang, Xiao
core   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

The impact of endogenous annexin A1 on glucocorticoid control of in ammatory arthritis [PDF]

, 2012
This work was supported by a Wellcome Trust (UK) project grant 083551. SMO is funded by Fundação de Amparo à Pesquisa do Estado de São Paulo – FAPESP (Grant 2011/00128-1) and Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq (Grant ...
Acquisto, FD, Girol, AP, Gray, M, Kornerup, KN, Oliani, SM, Patel, HB, Perretti, M, Pitzalis, C, Sampaio, ALF, Seed, MP   +9 more
core   +2 more sources