Results 11 to 20 of about 2,989,463 (164)
Lysophosphatidic Acid Signaling through the Lysophosphatidic Acid-1 Receptor Is Required for Alveolarization [PDF]
American Journal of Respiratory Cell and Molecular Biology, 2016 Abstract Lysophosphatidic acid (LPA) signaling through one of its receptors, LPA1, contributes to both the development and the pathological remodeling after injury of many organs. Because we found previously that LPA–LPA1 signaling contributes to pulmonary fibrosis, here we investigated whether this pathway is also involved in lung ...
Funke, Manuela +14 more
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Lysophosphatidic acid receptors in cancer pathobiology. [PDF]
Histology and histopathology, 2014 Lysophosphatidic acid (LPA) receptors (LPA₁ to LPA₆) are G protein-coupled transmembrane and mediate a variety of biological responses through the binding of LPA, such as cell proliferation, migration, morphogenesis and differentiation. Previously, high secretion levels of LPA were found in blood and ascites from patients with aggressive ovarian cancer.
Tsujiuchi, Toshifumi +4 more
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LPAR2 (lysophosphatidic acid receptor 2) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013 Review on LPAR2 (lysophosphatidic acid receptor 2), with data on DNA, on the protein encoded, and where the gene is implicated.
Knowlden, S, Georas, S
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LPAR1 (lysophosphatidic acid receptor 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on LPAR1 (lysophosphatidic acid receptor 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Murph, MM, Radhakrishna, H
openaire +4 more sources
Optical Control of Lysophosphatidic Acid Signaling [PDF]
, 2020 Lysophosphatidic acid (LPA) is a phospholipid that acts as an extracellular signaling molecule and activates the family of lysophosphatidic acid receptors (LPA1-6).
Citir, Mevlut +11 more
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Lysophosphatidic acid (LPA) and its Receptors: Role in Airway Inflammation and Remodeling [PDF]
, 2013 Lysophosphatidic acid (LPA), a simple bioactive phospholipid, is present in biological fluids such as plasma and bronchoalveolar lavage (BAL). It appears to have both pro- and anti-inflammatory role in inflammatory lung diseases.
Yutong Zhao (356724) +1 more
core +6 more sources
Linking medicinal cannabis to autotaxin–lysophosphatidic acid signaling
Life Science Alliance, 2023 The authors show that Δ9-trans-tetrahydrocannabinol, the main psychoactive compound in medicinal cannabis, could be considered as a therapeutic agent by inhibiting autotaxin–lysophosphatidic acid production. Autotaxin is primarily known for the formation
Mathias C Eymery +2 more
doaj +1 more source
Cells, 2021 Lysophosphatidic acid (LPA) is a bioactive lipid mediator primarily derived from membrane phospholipids. LPA initiates cellular effects upon binding to a family of G protein-coupled receptors, termed LPA receptors (LPAR1 to LPAR6).
Yu-Hsuan Lin +2 more
doaj +1 more source
International Journal of Reproductive BioMedicine, 2022 Background: Lysophosphatidic acid (LPA) contributes to follicular activation, oocyte maturation, in vitro fertilization, and embryo implantation. Objective: This study was designed to evaluate the effects of LPA to improve the development of isolated ...
Neda Abedpour +2 more
doaj +1 more source
Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]
, 2006 Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
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