Lysophospholipid S1P Receptors in Models of Multiple Sclerosis
Lysophospholipids are small, signaling lipids that are best known through the chemical species sphingosine 1‐phosphate (S1P) and lysophosphatidic acid (LPA). These molecules have been implicated in an increasingly broad range of physiological and pathophysiological roles with therapeutic potential and mediated ...
openaire +1 more source
Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174. [PDF]
Liu G, Li X, Wang Y, Zhang X, Gong W.
europepmc +1 more source
Fingolimod for Multiple Sclerosis: Mechanism of Action, Clinical Outcomes, and Future Directions [PDF]
The oral sphingosine 1-phosphate receptor (S1PR) modulator fingolimod functionally antagonizes S1PR hereby blocking lymphocyte egress from secondary lymphoid organs to the peripheral blood circulation. This results in a reduction in peripheral lymphocyte
Derfuss, Tobias +2 more
core
A protocol for RCT for an assessing the relative effectiveness of Tysabri vs. Gilenya in the treatment of RRMS [PDF]
Δεληγιάννη, Γεωργία
core +1 more source
Effects of lysophospholipid supplementation in diets with different oil sources on broiler performance under heat stress. [PDF]
Mohiti-Asli M +4 more
europepmc +1 more source
Novel insights into the lipid signalling in human spermatozoa. [PDF]
Serafini S, O'Flaherty C.
europepmc +1 more source
Lipidomic profiling reveals systemic serum lipid remodeling induced by dexamethasone in mice. [PDF]
Zhang A, Wang Z, Ji J.
europepmc +1 more source
ATP-release pannexin channels are gated by lysophospholipids. [PDF]
Henze E +11 more
europepmc +1 more source
The Role of Lysophospholipid Metabolites LPC and LPA in the Pathogenesis of Chronic Obstructive Pulmonary Disease. [PDF]
Zhou Q, Chen Y, Liang Y, Sun Y.
europepmc +1 more source
New insights into the crosstalk between endocannabinoids and sphingosine-1-phosphate. [PDF]
Rapino C +5 more
europepmc +1 more source

