Results 91 to 100 of about 31,255 (208)
Non-genomic actions of aldosterone: From receptors and signals to membrane targets. [PDF]
In tissues which express the mineralocorticoid receptor (MR), aldosterone modulates the expression of membrane targets such as the subunits of the epithelial Na(+) channel, in combination with important signalling intermediates such as serum and ...
Dooley, Ruth +2 more
core +1 more source
Intramyocardial gene silencing by interfering RNA [PDF]
RNAi is a widely used methodology for gene silencing. The action mechanism of siRNA molecules has been well studiedin recent years, and the technique has been optimized in terms of safety and effectiveness. Cardiovascular diseases havea high incidence in
Brea, María Soledad +2 more
core +1 more source
Cardiorenal fibrosis is a common feature of chronic cardiovascular disease and recent data suggests that cytokines and chemokines may also drive fibrosis.
Bing H. Wang +6 more
doaj +1 more source
Influence mechanisms of mineralocorticoid receptor antagonist (spironolactone) among elderly patients with chronic heartfailure against ischemic disease [PDF]
It was determined that a significant positive dynamics of TNF-synthesis suppression by 67.0% (p 0.0001) was established in the 4th group of patients taking combined therapy with the blocker of mineralocorticoid receptors with ...
Gorelik, S. G. +4 more
core
Effect of spironolactone on pain responses in mice [PDF]
The effects of spironolactone, a non-selective aldosterone antagonist, were examined on thermally-induced pain using the hot-plate and tail-flick tests, on hemogenic pain induced by intraplantar capsaicin, on electrically-induced pain, on visceral ...
Abdel-Salam, Omar M.E. +2 more
core
Cell-specific mineralocorticoid receptors: future therapeutic targets for stroke?
Quynh N Dinh +3 more
doaj +1 more source
Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta-Analysis. [PDF]
Juszczak GR.
europepmc +1 more source

