Results 81 to 90 of about 31,255 (208)

Effects of Mineralocorticoid Receptors Blockade on FearMemory Reconsolidation in Rats

open access: yesBasic and Clinical Neuroscience, 2011
Reconsolidation memory is defined as a process in which the retrieval of a previously consolidated memory returns to a labile state which is then subject to stabilization.
Ali Rashidy-Pour   +3 more
doaj   +2 more sources

Therapeutic potential of finerenone for diabetic cardiomyopathy: focus on the mechanisms

open access: yesDiabetology & Metabolic Syndrome
Diabetic cardiomyopathy (DCM) is a kind of myocardial disease that occurs in diabetes patients and cannot be explained by hypertensive heart disease, coronary atherosclerotic heart disease and other heart diseases. Its pathogenesis may be closely related
Jing Wang   +6 more
doaj   +1 more source

THE USE OF MINERALOCORTICOID RECEPTOR ANTAGONISTS IN THE PRE VENTION OF ATRIAL FIBRILLATION

open access: yesАрхивъ внутренней медицины, 2019
Atrial fibrillation (AF) is one of the most common cardiac rhythm disorders. Its prevalence is about 1 % in the general population and exceeds 7 % in individuals older than 60 years of age.
N. T. Vatutin   +3 more
doaj   +1 more source

Hsp90 blockers inhibit adipocyte differentiation and fat mass accumulation.

open access: yesPLoS ONE, 2014
Geldanamycin derivatives are benzoquinone ansamycin antibiotics that bind to Hsp90 and alter its function. The alteration of Hsp90 activity limits some cellular hormonal responses by inhibiting nuclear receptors activation. The nuclear receptors activity,
Sébastien Desarzens   +4 more
doaj   +1 more source

Behavioral stress induces regionally-distinct shifts of brain mineralocorticoid and glucocorticoid receptor levels

open access: yesFrontiers in Behavioral Neuroscience, 2014
Mineralocorticoid and glucocorticoid receptors (MRs and GRs) mediate the impact of stress on brain function primarily by affecting gene transcription in the cell nucleus. In vitro studies using hippocampal neurons indicate that MRs and GRs translocate to
Dorian eCaudal   +5 more
doaj   +1 more source

Role of the Renin-Angiotensin System and Aldosterone on Cardiometabolic Syndrome

open access: yesInternational Journal of Hypertension, 2011
Aldosterone facilitates cardiovascular damage by increasing blood pressure and through different mechanisms that are independent of its effects on blood pressure.
P. Stiefel   +3 more
doaj   +1 more source

Glucocorticoid and mineralocorticoid receptors and corticosteroid homeostasis are potential targets for endocrine-disrupting chemicals

open access: yesEnvironment International, 2019
Endocrine-disrupting chemicals (EDCs) have received significant concern, since they ubiquitously exist in the environment and are able to induce adverse health effects on human and wildlife. Increasing evidence shows that the glucocorticoid receptor (GR)
Jianyun Zhang   +4 more
doaj   +1 more source

11-Deoxycorticosterone (DOC)’s Action on the Gill Osmoregulation of Juvenile Rainbow Trout (Oncorhynchus mykiss)

open access: yesBiology
In aquaculture, stress can negatively affect fish growth. For years, the cortisol hormone has been thought to play both glucocorticoid and mineralocorticoid functions. Nevertheless, recent research has suggested that 11-deoxycorticosterone (DOC) released
Rodrigo Zuloaga   +4 more
doaj   +1 more source

Steroid Receptors and Vertebrate Evolution

open access: yes, 2019
Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago.
Baker, Michael E.
core  

Estado Confusional Agudo após Corticoterapia Inalada [PDF]

open access: yes, 2017
Background: The connection between corticotherapy and neuropsychiatric symptoms is widely known, being one of the first questions we need to assess when presenting with first episode psychiatric symptoms or confusional state.
Monteiro, J   +4 more
core  

Home - About - Disclaimer - Privacy