Results 181 to 190 of about 830 (216)

At long last: identification of an oocyte mitogen receptor

Trends in Cell Biology, 2001
It might come as a surprise that, despite the profusion of receptor-focused research and the keen interest of the medical community in understanding the intricacies of reproductive biology, a receptor responsible for activating oocyte meiotic maturation had not been described in a single organism until the end of the year 2000.
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Mitogenic effect of retinoid X receptor agonists in rat liver

Biochemical Pharmacology, 1997
(E)-2-[2-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl) propen-1-yl]-4-thiophenecarboxylic acid (AGN 191701) and other retinoid X receptor (RXR)-selective agonists were observed to cause hepatomegaly in rats. The purpose of the present study was to understand the biochemical basis of RXR agonist-induced hepatomegaly.
A M, Standeven, M, Escobar, R L, Beard, Y D, Yuan, R A, Chandraratna   +4 more
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Transferrin Receptors on Mitogen‐Stimulated Human Thymus‐Derived Lymphocytes

Scandinavian Journal of Immunology, 1982
The appearance of transferrin receptors on mitogen‐stimulated human thymus‐derived (T) lymphocytes was studied. When indirect immunofluorescence with immunoadsorbent‐purified antitransferrin antibodies was used, ∼ 10% of resting T cells were stained. This proportion increased to 50–80% of the cells 3–4 days after stimulation with the mitogenic lectins ...
M L, Hammarström, B, Axelsson, M, Ivansen, S, Hammarström, P, Perlmann   +4 more
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Expression of receptors for iga on mitogen‐stimulated human t lymphocytes

European Journal of Immunology, 1988
AbstractThis study demonstrates that activation of human peripheral blood mononuclear cells (PBMC) by the T cell mitogens phytohemagglutinin (PHA) and concanavalin A (Con A) induces the expression of receptors for IgA without addition of IgA to the culture medium.
I, Millet, G, Panaye, J P, Revillard
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Regulation of Mitogen-Activated Protein Kinase Pathways by Catecholamine Receptors

1997
Publisher Summary Until recently little has been known about the mechanisms of mitogenic signal transduction employed by receptors that couple to heterotrimeric G-proteins (GRs). These receptors participate in the regulation of cell proliferation in both physiological and pathophysiological states, and in cellular transformation in some, mostly ...
L M, Luttrell, T, van Biesen, B E, Hawes, G J, Della Rocca, D K, Luttrell, R J, Lefkowitz   +5 more
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Demonstration of receptors for a PDGF-like mitogen on human osteosarcoma cells

Biochemical and Biophysical Research Communications, 1985
U-2 OS human osteosarcoma cells synthesize, process and secrete a platelet-derived growth factor (PDGF)-like mitogen. Incubation of these cells with 1 mM suramin unmasks PDGF receptor sites which are normally occupied or down regulated by the secreted endogenous PDGF-like mitogen.
D T, Graves, A J, Owen, H N, Antoniades
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Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

Science, 1995
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER activation function 1 (AF-1). This Ser 118 is phosphorylated by mitogen-activated protein kinase (MAPK) in vitro and in cells treated with epidermal growth factor (EGF) and insulin-like ...
Kato, Shigeaki, Endoh, Hideki, Masuhiro, Yoshikazu, Kitamoto, Takuya, Uchiyama, Shimami, Sasaki, Haruna, Masushige, Shoichi, Gotoh, Yukiko, Nishida, Eisuke, Kawashima, Hiroyuki, Metzger, Daniel, Chambon, Pierre   +11 more
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Lymphocyte receptors for polyclonal T mitogens

Cellular Immunology, 1982
Jean J. Favero, Ian L. Gordon, John W. Parker, Richard L. O'Brien   +3 more
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Astrocyte Mitogen Inhibitor Related to Epidermal Growth Factor Receptor

Science, 1988
Epidermal growth factor (EGF) is a well-characterized polypeptide hormone with diverse biological activities, including stimulation of astrocyte division. A soluble astrocyte mitogen inhibitor, immunologically related to the EGF receptor, is present in rat brain.
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ESCRT proteins, endosome organization and mitogenic receptor down-regulation

Biochemical Society Transactions, 2009
Mitogenic tyrosine kinase receptors such as the EGFR (epidermal growth factor receptor) are endocytosed once they are activated at the cell surface. After reaching the early endosome, they are ubiquitinated within their cytosolic domain and are consequently sorted away from recycling receptors.
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