Atypical Presentation of Anti‐NMDAR Encephalitis in an Elderly Male With Dominated Memory Impairment From Damascus Hospital [PDF]
Clinical Case ReportsAnti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is a rare but serious autoimmune disorder that is typically characterized by a broad spectrum of psychiatric and neurological symptoms.
Hamza Warda +6 more
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Protein quality control of N-methyl-D-aspartate receptors
Frontiers in Cellular Neuroscience, 2022 N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated cation channels that mediate excitatory neurotransmission and are critical for synaptic development and plasticity in the mammalian central nervous system (CNS). Functional NMDARs typically form
Taylor M. Benske +2 more
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Roles of N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy
Frontiers in Molecular Neuroscience, 2022 Epilepsy is one of the most common neurological disorders characterized by recurrent seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N-methyl-D-aspartate receptors (NMDARs) play an important role in abnormal ...
Shuang Chen +5 more
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Frontiers in Psychiatry, 2023 BackgroundAntibodies against N-methyl-D-aspartate receptors are the most commonly identified cause of autoimmune encephalitis. While predominantly associated with malignancies, cases of anti-N-methyl-D-aspartate receptor autoimmune encephalitis have been
Thomas Hainmueller +4 more
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The Journal of Poultry Science, 2020 L-Pipecolic acid is an intermediate of L-lysine catabolism. Its central injection exerted a hypnotic effect on the brain, which was partially mediated by the activation of γ-aminobutyric acid-A and γ-aminobutyric acid-B receptors. L-Proline has also been
Asako Shigemura +2 more
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Amiloride but not memantine reduces neurodegeneration, seizures and myoclonic jerks in rats with cardiac arrest-induced global cerebral hypoxia and reperfusion. [PDF]
PLoS ONE, 2013 It has been reported that both activation of N-methyl-D-aspartate receptors and acid-sensing ion channels during cerebral ischemic insult contributed to brain injury.
Kwok Keung Tai, Daniel D Truong
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N-Methyl-D-Aspartate Receptors in Hematopoietic Cells: What Have We Learned?
Frontiers in Physiology, 2020 The N-methyl-D-aspartate receptor (NMDAR) provides a pathway for glutamate-mediated inter-cellular communication, best known for its role in the brain but with multiple examples of functionality in non-neuronal cells.
Maggie L. Kalev-Zylinska +6 more
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In silico investigation on the probable macromolecular drug targets involved in the anti-schizophrenia activity of Nardostachys jatamansi [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 Existing medications i.e. the antipsychotic drugs are known to be effective in treating only the positive symptoms of schizophrenia, while being ineffective on negative and cognitive symptoms of the disease.
Foong Xi Wei +2 more
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Anti-N-methyl-D-aspartate receptor encephalitis: analysis of three cases
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Objective To explore the clinical features, diagnosis, treatment and prognosis of patients with anti-N-methyl-D-aspartate (NMDA) receptor encephalitis.
Ya-nan TIAN
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Research progress of N⁃methyl⁃D⁃aspartate receptor GRIN2A gene variations and epilepsy
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 In recent years, with the rapid development of gene sequencing technology, a variety of epilepsy pathogenic genes have been discovered, among which GRIN2A gene variations encoding the neurotransmitter N⁃methyl⁃D⁃aspartate receptor (NMDAR) are closely ...
TANG Wei⁃ting, XIAO Bo
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