Results 1 to 10 of about 155,151 (336)

Roles of N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy [PDF]

Frontiers in Molecular Neuroscience, 2022
Epilepsy is one of the most common neurological disorders characterized by recurrent seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N-methyl-D-aspartate receptors (NMDARs) play an important role in abnormal ...
Shuang Chen, Da Xu, Liu Fan, Zhi Fang, Xiufeng Wang, Man Li   +5 more
doaj   +4 more sources

Protein quality control of N-methyl-D-aspartate receptors

Frontiers in Cellular Neuroscience, 2022
N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated cation channels that mediate excitatory neurotransmission and are critical for synaptic development and plasticity in the mammalian central nervous system (CNS). Functional NMDARs typically form
Taylor M. Benske, Ting-Wei Mu, Ya-Juan Wang   +2 more
doaj   +3 more sources

Atypical Presentation of Anti‐NMDAR Encephalitis in an Elderly Male With Dominated Memory Impairment From Damascus Hospital [PDF]

Clinical Case Reports
Anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is a rare but serious autoimmune disorder that is typically characterized by a broad spectrum of psychiatric and neurological symptoms.
Hamza Warda, Ola Emad Alasmar, Abdulkareem Muhammad Wardeh, Ali Mohammad Ibrahem, Esraa Alsaadi, Heba Alsamara, Anas Jouhar   +6 more
doaj   +2 more sources

Case report: Anti N-methyl-D-aspartate autoimmune encephalitis following a mildly symptomatic COVID-19 infection in an adolescent male

Frontiers in Psychiatry, 2023
BackgroundAntibodies against N-methyl-D-aspartate receptors are the most commonly identified cause of autoimmune encephalitis. While predominantly associated with malignancies, cases of anti-N-methyl-D-aspartate receptor autoimmune encephalitis have been
Thomas Hainmueller, Lambert Lewis, Lambert Lewis, Tzvi Furer, Tzvi Furer   +4 more
doaj   +1 more source

Intracerebroventricular Injection of L-Pipecolic Acid Exerts Hypnotic Effects Without Activating NMDA Receptors in Neonatal Chicks under Social Isolation-induced Stress

The Journal of Poultry Science, 2020
L-Pipecolic acid is an intermediate of L-lysine catabolism. Its central injection exerted a hypnotic effect on the brain, which was partially mediated by the activation of γ-aminobutyric acid-A and γ-aminobutyric acid-B receptors. L-Proline has also been
Asako Shigemura, Vishwajit S. Chowdhury, Mitsuhiro Furuse   +2 more
doaj   +1 more source

A diagnostic dilemma: Laparoscopic approach in treating ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis

Philippine Journal of Obstetrics and Gynecology, 2021
A 24-year-old nulligravida who presented with seizures and behavioral changes with prodrome of flu-like symptoms was initially treated as a case of viral encephalitis.
Finella Marie G. Leonido, Maria Czarina V Mendoza   +1 more
doaj   +1 more source

Amiloride but not memantine reduces neurodegeneration, seizures and myoclonic jerks in rats with cardiac arrest-induced global cerebral hypoxia and reperfusion. [PDF]

PLoS ONE, 2013
It has been reported that both activation of N-methyl-D-aspartate receptors and acid-sensing ion channels during cerebral ischemic insult contributed to brain injury.
Kwok Keung Tai, Daniel D Truong
doaj   +1 more source

The NMDA agonist D-cycloserine facilitates fear memory consolidation in humans [PDF]

, 2009
Animal research suggests that the consolidation of fear and extinction memories depends on N-methyl D-aspartate (NMDA)- type glutamate receptors.
Amaral, Anthony, Ashburner, Bauer, Beatrice Holt, Benedetto De Martino, Blair, Bond, Bouton, Buchel, Carmichael, Carter, Christian Büchel, Corcoran, Corcoran, Critchley, Davis, Deichmann, Deichmann, Delamater, Duvernoy, Ekman, Frankland, Friston, Friston, Gould, Guastella, Heresco-Levy, Hetem, Hofmann, Honey, Izquierdo, Ji, Kalisch, Kalisch, Kalisch, Kalisch, Karcz-Kubicha, Kim, Klodzinska, Kushner, LaBar, LaBar, Ledgerwood, Lee, Mao, Maren, Martin, McGaugh, Morris, Myers, Parwani, Pavlov, Penny, Phelps, Predrag Petrovic, Raffael Kalisch, Raymond J. Dolan, Ressler, Rodrigues, Rubin, Runyan, Scavio, Schafe, Seymour, Sheinin, Sotres-Bayon, Spielberger, Stefan Klöppel, Stewart, Takehara, Trevisan, van Berckel, Vervliet, Walker, Yang, Zhu, Zorawski   +77 more
core   +2 more sources

Anti-N-methyl-D-aspartate Receptor Encephalitis [PDF]

Cureus, 2019
Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis is an underrecognized encephalitis that may be mistaken for a wide variety of mental illnesses and causes of delirium. This syndrome is predominantly present in young females presenting with acute psychotic episodes, autonomic instability, and neurologic abnormalities.
Tanquary, Gregory, Fraser, William, Bowers, Kaitlin M   +2 more
openaire   +2 more sources

The effects of AMPA receptor blockade on resting magnetoencephalography recordings [PDF]

, 2017
The ionotropic N-methyl-D-aspartate and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors of the glutamatergic neurotransmitter system are of fundamental importance to healthy brain function.
Khalid, Hamandi, Muthukumaraswamy, Suresh D, Routley, Bethany, Singh, Krishna   +3 more
core   +1 more source