Results 181 to 190 of about 156,800 (338)

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

open access: yesVIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu   +8 more
wiley   +1 more source

Glutamate-Dependent Dynamic DNA Methylation Regulates Excitatory Amino Acid Transporters in Bergmann Glia Cells: Role of AMPA Receptors. [PDF]

open access: yesASN Neuro
Oyetayo BO   +11 more
europepmc   +1 more source

Critical evaluation of three cryo‐EM structures of particulate methane monooxygenase by quantum refinement

open access: yesActa Crystallographica Section D, EarlyView.
We have studied the copper sites in three cryogenic electron‐microscopy structures of particulate methane monooxygenase with quantum refinement. We show that the CuA, CuC and CuD sites are correctly modelled and that the CuB site is mononuclear in all structures, whereas we find no support for copper in the suggested trinuclear active site or two sites
Gayathri Yuvaraj   +4 more
wiley   +1 more source

Long-term potentiation and the role of N-methyl-d-aspartate receptors

open access: yesBrain Research, 2015
A. Volianskis   +5 more
semanticscholar   +1 more source

Mechanism of Ammonia‐Induced Brain Damage in Chinese Striped‐Necked Turtle (Mauremys sinensis)

open access: yesIntegrative Zoology, EarlyView.
High levels of ammonia disrupt the integrity of the brain barrier in Mauremys sinensis, leading to tissue edema. This, in turn, triggers a series of cascade reactions, including disturbances in neurotransmitter levels, particularly glutamate, which might further exacerbate the neurotoxic effects.
Yunjuan Xiao   +6 more
wiley   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian   +3 more
wiley   +1 more source

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