Results 181 to 189 of about 115,612 (189)
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Opiate physical dependence and N-methyl-d-aspartate receptors
European Journal of Pharmacology, 2004The present review focused the involvement of N-methyl-D-aspartate (NMDA) receptors in morphine physical dependence. The increased levels of extracellular glutamate, NMDA receptor zeta subunit (NR1) mRNA, NMDA receptor epsilon 1 subunit (NR2A) protein, phosphorylated Ca(2+)/calmodulin kinase II (p-CaMKII) protein, c-fos mRNA, c-Fos protein, are ...
Yukihiro Noda, Toshitaka Nabeshima
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Polyamine Regulation of N-Methyl-D-Aspartate Receptor Channels
Annual Review of Pharmacology and Toxicology, 1995Endogenous polyamines such as spermine and spermidine have multiple effects in the central nervous system and have been suggested to be neurotransmitters or neuromodulators. One effect of the polyamines is to regulate the activity of the N-methyl-D-aspartate receptor (NMDAR) channel subtype of glutamate receptor channels.
David M. Rock, Robert L. Macdonald
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N-methyl-d-aspartate (NMDA) receptors are inactivated by trypsin
Brain Research, 1988Acute isolation of hippocampal CA3 pyramidal cells using trypsin produces neurons which respond to kainate and quisqualate but not N-methyl-D-aspartate (NMDA). Incubation of 6- to 12-day-old cultured hippocampal neurons or slices of pyriform cortex with trypsin irreversibly removes the NMDA responses normally present without significant effect on ...
Nobuaki Hori +4 more
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N-Methyl-D-Aspartate Receptor in Human Prostate Cancer
Journal of Membrane Biology, 2005Expression of the N-methyl-D-aspartate receptor (NMDAr) and its involvement in cellular proliferation is well-known in tumors of neuronal tissue, such as glioma and neuroblastoma. We have investigated NMDAr expression in the normal, hyperplastic and neoplastic human prostate by immunohistochemistry. Low stromal NMDAr immunostaining was observed in 2 of
M. Abdul, N. Hoosein
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Principles of N-Methyl-d-aspartate Receptor Allosteric Modulation
Molecular Pharmacology, 2005N-methyl-D-aspartate (NMDA) receptors are glutamate-gated ion channels with complex participation in synaptic transmission, integration, and plasticity. They are highly permeable to Ca(2+), activate with characteristic kinetics, and generate currents with distinct amplitudes according to stimulation frequency.
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N-Methyl-D-Aspartate Receptor Autoantibodies in Psychiatric Illness
Biological Psychiatry, 2016Belinda R Lennox +2 more
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N-methyl-D-aspartate receptor antibody-mediated encephalitis
British Journal of Hospital Medicine, 2012Sachin Mehta +4 more
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N-methyl-D-aspartic acid receptor structure and function
Physiological Reviews, 1994M. L. Mayer, Chris J. McBain
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