Results 11 to 20 of about 115,612 (189)

Anti-N-methyl-D-aspartate Receptor Encephalitis [PDF]

Cureus, 2019
Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis is an underrecognized encephalitis that may be mistaken for a wide variety of mental illnesses and causes of delirium. This syndrome is predominantly present in young females presenting with acute psychotic episodes, autonomic instability, and neurologic abnormalities.
Gregory Tanquary, William Fraser, Kaitlin M Bowers   +2 more
openaire   +3 more sources

Anti-N-Methyl-D-Aspartate Receptor Encephalitis

Pediatric Neurology Briefs, 2013
Investigators at Universities of Barcelona, Pennsylvania, Oviedo, and Valencia, and the Spanish NMDAR Encephalitis Work Group report the clinical features of 20 pediatric patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis seen in a single center in Spain in the last 4 years.
Kenneth Nugent, Charoen Mankongpaisarnrung, Ragesh Panikkath, Ebtesam Islam, Zachary Mulkey, Sian Yik Lim   +5 more
  +10 more sources

Pharmacology of triheteromeric N-Methyl-d-Aspartate Receptors [PDF]

Neuroscience Letters, 2016
The N-Methyl-D-Aspartate Receptors (NMDARs) are heteromeric cation channels involved in learning, memory, and synaptic plasticity, and their dysregulation leads to various neurodegenerative disorders. Recent evidence has shown that apart from the GluN1/GluN2A and GluN1/GluN2B diheteromeric ion channels, the NMDAR also exists as a GluN1/GluN2A/GluN2B ...
Kasper B. Hansen, John Cheriyan, Rashna D. Balsara, Francis J. Castellino   +3 more
openaire   +3 more sources

The NMDA agonist D-cycloserine facilitates fear memory consolidation in humans [PDF]

, 2009
Animal research suggests that the consolidation of fear and extinction memories depends on N-methyl D-aspartate (NMDA)- type glutamate receptors.
Amaral, Anthony, Ashburner, Bauer, Beatrice Holt, Benedetto De Martino, Blair, Bond, Bouton, Buchel, Carmichael, Carter, Christian Büchel, Corcoran, Corcoran, Critchley, Davis, Deichmann, Deichmann, Delamater, Duvernoy, Ekman, Frankland, Friston, Friston, Gould, Guastella, Heresco-Levy, Hetem, Hofmann, Honey, Izquierdo, Ji, Kalisch, Kalisch, Kalisch, Kalisch, Karcz-Kubicha, Kim, Klodzinska, Kushner, LaBar, LaBar, Ledgerwood, Lee, Mao, Maren, Martin, McGaugh, Morris, Myers, Parwani, Pavlov, Penny, Phelps, Predrag Petrovic, Raffael Kalisch, Raymond J. Dolan, Ressler, Rodrigues, Rubin, Runyan, Scavio, Schafe, Seymour, Sheinin, Sotres-Bayon, Spielberger, Stefan Klöppel, Stewart, Takehara, Trevisan, van Berckel, Vervliet, Walker, Yang, Zhu, Zorawski   +77 more
core   +2 more sources

Cardiac N-methyl d-aspartate Receptors as a Pharmacological Target [PDF]

Journal of Cardiovascular Pharmacology, 2016
Abstract: This study focuses on characterization of the cardiac N-methyl d-aspartate receptors (NMDARs) as a target for endogenous and synthetic agonists and antagonists. Using isolated perfused rat hearts, we have shown that intracoronary administration of the NMDAR agonists and antagonists has a pronounced effect on autonomous heart ...
Makhro, Asya, Tian, Qinghai, Kaestner, Lars, Kosenkov, Dmitry, Faggian, Giuseppe, Gassmann, Max, Schwarzwald, Colin, Bogdanova, Anna   +7 more
openaire   +4 more sources

The effects of AMPA receptor blockade on resting magnetoencephalography recordings [PDF]

, 2017
The ionotropic N-methyl-D-aspartate and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors of the glutamatergic neurotransmitter system are of fundamental importance to healthy brain function.
Khalid, Hamandi, Muthukumaraswamy, Suresh D, Routley, Bethany, Singh, Krishna   +3 more
core   +1 more source

Role of N-methyl-D-aspartate receptors in action-based predictive coding deficits in schizophrenia [PDF]

, 2017
Published in final edited form as:Biol Psychiatry. 2017 March 15; 81(6): 514–524. doi:10.1016/j.biopsych.2016.06.019.BACKGROUND: Recent theoretical models of schizophrenia posit that dysfunction of the neural mechanisms subserving predictive coding ...
Ford, Judith M., Gunduz-Bruce, Handan, Jaeger, Judith, Kort, Naomi S., Krystal, John H., Mathalon, Daniel H., Reinhart, Robert M.G., Roach, Brian J.   +7 more
core   +1 more source

Anti-N-Methyl-d-Aspartate Receptor Encephalitis

Pediatrics & Neonatology, 2011
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a treatment-responsive encephalitis associated with anti-NMDA receptor antibodies, which bind to the NR1/NR2 heteromers of the NMDA receptors. It is a highly characteristic syndrome evolving in five stages: the prodromal phase (viral infection-like symptoms), psychotic phase, unresponsive phase,
Ning-Hui Foo, Te-Yu Hung, Ming-Chi Lai
openaire   +4 more sources

NR2A- and NR2B-containing NMDA Receptors in the Prelimbic Medial Prefrontal Cortex Differentially Mediate Trace, Delay, and Contextual Fear Conditioning [PDF]

, 2013
Activation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association ...
Gilmartin, Marieke R., Helmstetter, Fred J., Kwapis, Janine L.   +2 more
core   +2 more sources

An expanding range of targets for kynurenine metabolites of tryptophan [PDF]

, 2013
The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail, Stone, Trevor W., Stoy, Nicholas   +2 more
core   +1 more source