This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre +3 more
wiley +1 more source
Glial-mediated immune modulation in glaucomatous neurodegeneration: mechanisms and therapeutic implications. [PDF]
Zong F, You J, Wu H, Wang X.
europepmc +1 more source
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel +5 more
wiley +1 more source
Midkine as a therapeutic node in NF1-driven neuro‑oncology: Biology, biomarkers, and translational strategies. [PDF]
Nair HB, Subramani R, Lakshmanaswamy R.
europepmc +1 more source
Directional Liquid Transport Enabled pH‐Responsive Hierarchical Composite for Enhanced Wound Healing
A hierarchical composite with a gradient architecture transitioning from hydrophobic to hydrophilic layers integrates diode‐like liquid transport, efficient water absorption, breathability, and mechanical robustness. This device enables a multifunctional therapeutic platform with pH‐responsive dual‐drug release, providing synergistic anti‐inflammatory ...
Baolin Wang +5 more
wiley +1 more source
Adipose Tissue and Central Nervous System Crosstalk: Roles in Pain and Cognitive Dysfunction. [PDF]
Li J +6 more
europepmc +1 more source
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
Unveiling the Role of CCL3: A Driver of CIPN in Colon Cancer Patients? [PDF]
Luzac I, Regalado CR, Balogh M.
europepmc +1 more source
Neurocardiac Crosstalk: Sympathetic Remodeling and Arrhythmogenesis After Myocardial Infarction. [PDF]
Yu T.
europepmc +1 more source
The Histamine-Associated Inflammatory Landscape of Endometriosis: Molecular Profiling of HDC, HRH1-HRH4, and Cytokines Across Lesion Subtypes. [PDF]
Velho RV +5 more
europepmc +1 more source

