Results 71 to 80 of about 21,072,923 (152)

Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors

, 2008
Peptide receptors are often overexpressed in tumors, and they may be targeted in vivo. We evaluated neuropeptide Y (NPY) receptor expression in 131 primary human brain tumors, including gliomas, embryonal tumors, meningiomas, and pituitary adenomas, by ...
Reubi, Jean Claude, Körner, Meike
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Solubilization and characterization of active neuropeptide-Y receptors from rabbit kidney [PDF]

, 1990
Active neuropeptide Y receptors were solubilized from rabbit kidney membranes using the zwitterionic detergent 3-[ (3-cholamidopropy l)dimethylammonio ]- 1-propanesulfonic acid (CHAPS).
Gimpl, G., Gerstberger, R., Klotz, Karl-Norbert, Lang, R. E., Mauss, U.   +4 more
core   +2 more sources

Neuropeptide Y modulates the electrical activity of subfornical organ neurons

Current Research in Neurobiology
The subfornical organ (SFO) is a sensory circumventricular organ, lacking a blood-brain barrier. It is well-recognized as a key center for detection and integration of osmotic, ionic and hormonal signals for maintenance of hydromineral balance and ...
Lauren Shute, Mark Fry
doaj   +1 more source

Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia

Cell Reports, 2013
Human monogenic obesity syndromes, including Bardet-Biedl syndrome (BBS), implicate neuronal primary cilia in regulation of energy homeostasis. Cilia in hypothalamic neurons have been hypothesized to sense and regulate systemic energy status, but the ...
Alexander V. Loktev, Peter K. Jackson
doaj   +1 more source

The therapeutic effects of labetalol in chronic stress- and immuno-agonist-induced cough hypersensitivity and lung inflammation involve reducing interferon-γ-producing T lymphocytes

ERJ Open Research
Background Psychological stress correlates with chronic cough, which is often triggered by respiratory viruses. Chronic stress promotes sympathetic nerves to release norepinephrine and neuropeptide Y.
Tongtong Song, Fengying Li, Wenbin Ding, Dongting Xu, Shuirong Shen, Nanshan Zhong, Kefang Lai, Zheng Deng   +7 more
doaj   +1 more source

Cell Surface Protein Detection to Assess Receptor Internalization

Bio-Protocol, 2016
The migration of membrane receptors upon exposure to different stimulants/inhibitors is of great importance. Among others, the internalization of membrane receptors affects their accessibility to ligands and cell responsiveness to environmental cues ...
Magdalena Czarnecka, Joanna Kitlinska
doaj   +1 more source

Heterobivalent Dual-Target Peptide for Integrin-α_vβ₃ and Neuropeptide Y Receptors on Breast Tumor

Pharmaceuticals
Background/Objectives: Heterodimer peptides targeting more than one receptor can be advantageous, as tumors can simultaneously express more than one receptor type.
Aryel H. Ferreira, Caroline C. Real, Osvaldo Malafaia   +2 more
doaj   +1 more source

Smoking is Associated with Reduced Leptin and Neuropeptide Y Levels and Higher Pain Experience in Patients with Fibromyalgia

Mediators of Inflammation, 2014
Smoking deregulates neuroendocrine responses to pain supporting production of neuropeptide Y (NpY) by direct stimulation of nicotinic receptors or by inhibiting adipokine leptin.
Maria I. Bokarewa, Malin C. Erlandsson, Jan Bjersing, Mats Dehlin, Kaisa Mannerkorpi   +4 more
doaj   +1 more source

Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.

, 2010
Gene therapy using recombinant adeno-associated viral vectors overexpressing neuropeptide Y in the hippocampus exerts seizure-suppressant effects in rodent epilepsy models and is currently considered for clinical application in patients with intractable ...
Gøtzsche, Casper R, Elbrønd-Bek, Heidi, Merab Kokaia, Ängehagen, Mikael,, Woldbye, David P D, Olesen, Mikkel V, Nikitidou, Litsa,, Toft Sörensen, Andreas, Hansen, Thomas V O, Litsa Nikitidou, Ängehagen, Mikael, Thomas v. O. Hansen, Christiansen, Søren H, Olesen, Mikkel V., Kokaia, Merab, Andreas T. Sørensen, Kanter-Schlifke, Irene, Søren H. Christiansen, Hansen, Thomas v. O., Casper R. Gøtzsche, Kanter Schlifke, Irene,, Sørensen, Andreas Toft, Christiansen, Søren Hofman Oliveira, Kanter Schlifke, Irene, Irene Kanter-Schlifke, Kokaia, Merab,, Gøtzsche, Casper René, Nikitidou, Litsa, Woldbye, David Paul Drucker, David P. D. Woldbye, Mikael Ängehagen, Heidi Elbrønd-Bek, Toft Sörensen, Andreas,, Lund University., Mikkel V. Olesen   +34 more
core   +1 more source

O neuropeptídio Y (NPY) na medula espinhal medeia o efeito hiponociceptivo da ativação de receptores H1 histaminérgicos na articulação do joelho de ratos [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A histamina é encontrada no líquido sinovial de indivíduos saudáveis e pacientes com diversos tipos ...
Silva, Eduardo Souza
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