Results 131 to 140 of about 2,426,956 (334)

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Benigno, Arcangelo, Di Giovanni, Giuseppe, Muscat, Richard, Pierucci, Massimo, Pitruzzella, Alessandro, Valentino, Mario, Zammit, Christian   +6 more
core   +1 more source

Non‐Classical Nitrogen Promoters for Rhodium‐Catalyzed Reductive Hydroformylation: New Efficient Way to Access Polyols From Linseed Oil

European Journal of Lipid Science and Technology, EarlyView.
The reductive hydroformylation of linseed oil was carried out using a rhodium precursor associated with various nitrogen derivatives such as pyridines, imidazoles, trialkylamines, amidines, and guanidines. ABSTRACT The reductive hydroformylation reaction of polyunsaturated linseed oil using a rhodium precursor associated with a nitrogen compound from ...
Walid Abdallah, Michel Ferreira, Sylvain Laclef, David Mathiron, Serge Pilard, Rénato Froidevaux, Maxime De Sousa Lopes Moreira, Hervé Bricout, Eric Monflier, Sébastien Tilloy   +9 more
wiley   +1 more source

Fine‐Tuning Gramicidin S: How δ‐Phenylproline Affects Turns and Interaction with Membrane.

European Journal of Organic Chemistry, Accepted Article.
The introduction of a phenyl ring at the 5‐position of proline significantly impacts the conformation and membrane interactions of Gramicidin S. In this study, we investigate the effects of incorporating cis‐5‐phenyl‐L‐proline into Gramicidin S, focusing on its structural behavior and interaction with lipid bilayers. Using a homochiral model dipeptide,
Pedro Merino, Irene Sánchez-Burillo, Ana I. Jiménez, Tomás Tejero   +3 more
wiley   +1 more source

Nitrosamines as nicotinic receptor ligands [PDF]

Life Sciences, 2007
Nitrosamines are carcinogens formed in the mammalian organism from amine precursors contained in food, beverages, cosmetics and drugs. The potent carcinogen, NNK, and the weaker carcinogen, NNN, are nitrosamines formed from nicotine. Metabolites of the nitrosamines react with DNA to form adducts responsible for genotoxic effects. We have identified NNK
openaire   +3 more sources

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Rates and Equilibria for a Photoisomerizable Antagonist at the Acetylcholine Receptor of Electrophorus Electroplaques [PDF]

, 1985
Voltage-jump and light-flash experiments have been performed on isolated Electrophorus electroplaques exposed simultaneously to nicotinic agonists and to the photoisomerizable compound 2,2'-bis-[α-(trimethylammonium)methyl]-azobenzene (2BQ).
Erlanger, Bernard F., Krouse, Mauri E., Lester, Henry A., Wassermann, Norbert H.   +3 more
core   +1 more source

Nicotinic acetylcholine receptors and nicotine addiction: A brief introduction

Neuropharmacology, 2020
Ruthie E. Wittenberg, S. Wolfman, M. Biasi, J. Dani   +3 more
semanticscholar   +1 more source

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

Environmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz, Krittika Mittal, Na'im Temlock, Jessica Head, Niladri Basu   +4 more
wiley   +1 more source

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source

Nicotinic acetylcholine receptors and cancer

Biomedical Reports, 2016
Nicotine, the primary addictive constituent of cigarettes, is believed to contribute to cancer promotion and progression through the activation of nicotinic acetylcholine receptors (nAChRs), which are membrane ligand-gated cation channels. nAChRs activation can be triggered by the neurotransmitter Ach, or certain other biological compounds, such as ...
Xianguang Meng, Haiyan Song, Ningning Dang   +2 more
openaire   +4 more sources