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Interpretable multitask deep learning models for odor perception based on molecular structure. [PDF]
Curr Res Food SciIwata H.
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Structural analogs modulate olfactory and behavioral responses to a bile acid sex pheromone in sea lamprey (Petromyzon marinus). [PDF]
J Comp Physiol A Neuroethol Sens Neural Behav PhysiolScott AM, Li K, Riedy JJ, Li W.
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Cellular and Molecular Life Sciences (CMLS), 1999
Olfactory transduction begins with the binding of an odorous molecule to a protein receptor--odorant receptor--on the cell surface of olfactory neuron. Odorant receptors are encoded by a large gene family belonging to the superfamily of G-protein-coupled, seven-transmembrane-domain receptors. Since the identification of the receptor gene family in 1991,
H, Zhao, S, Firestein
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Olfactory transduction begins with the binding of an odorous molecule to a protein receptor--odorant receptor--on the cell surface of olfactory neuron. Odorant receptors are encoded by a large gene family belonging to the superfamily of G-protein-coupled, seven-transmembrane-domain receptors. Since the identification of the receptor gene family in 1991,
H, Zhao, S, Firestein
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Evolution of odorant receptors
BioEssays, 2000Odorant receptors (ORs) located in the nasal epithelium, at the ciliated surface of olfactory sensory neurons, represent the initial step of a transduction cascade that leads to odor detection. ORs form the largest and most diverse family of G-protein-coupled receptors (GPCRs).
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Ligand specificity of odorant receptors
Journal of Molecular Modeling, 2006Odorant receptors belong to class A of the G protein-coupled receptors (GPCRs) and detect a large number of structurally diverse odorant molecules. A recent structural bioinformatic analysis suggests that structural features are conserved across class A of GPCRs in spite of their low sequence identity.
Khafizov, K. +3 more
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INSECT ODOR AND TASTE RECEPTORS
Annual Review of Entomology, 2006▪ Abstract Insect odor and taste receptors are highly sensitive detectors of food, mates, and oviposition sites. Following the identification of the first insect odor and taste receptors in Drosophila melanogaster, these receptors were identified in a number of other insects, including the malaria vector mosquito Anopheles gambiae; the silk moth ...
Elissa A, Hallem +2 more
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2014
Odorant-receptor interactions constitute a key step in the olfactory detection of chemical compounds. Various studies support the combinatorial coding of olfaction, in which each odorant activates an array of odorant receptors and each odorant receptor is capable of recognizing multiple odorants, while large-scale studies involving numerous odorants ...
Xubo Su, Hiroaki Matsunami, Hanyi Zhuang
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Odorant-receptor interactions constitute a key step in the olfactory detection of chemical compounds. Various studies support the combinatorial coding of olfaction, in which each odorant activates an array of odorant receptors and each odorant receptor is capable of recognizing multiple odorants, while large-scale studies involving numerous odorants ...
Xubo Su, Hiroaki Matsunami, Hanyi Zhuang
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2016
Until now the odorant receptors are greatly underappreciated. Olfaction is very important for the live of humans and animals, especially animals depend more on olfaction than humans in many function such as to distinguish suitable food, to unfit foodstuff, to avoid dangers, to protect from enemies, to communicate that way, and to find a receptive mate.
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Until now the odorant receptors are greatly underappreciated. Olfaction is very important for the live of humans and animals, especially animals depend more on olfaction than humans in many function such as to distinguish suitable food, to unfit foodstuff, to avoid dangers, to protect from enemies, to communicate that way, and to find a receptive mate.
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Odorant–Receptor Interactions and Odor Percept: A Chemical Perspective
Chemistry & Biodiversity, 2008AbstractReceptor–ligand interaction models are generally based on a ‘lock and key’ concept. How far this holds true for olfactory receptors and odor molecules is currently uncertain. Here, we have investigated the response of a human olfactory receptor, OR1D2, to a broad array of odorants and found that there is no simple, direct correlation between a ...
Annika, Triller +6 more
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