Results 91 to 100 of about 25,455 (216)

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Systematic Review and Meta‐Analysis of Mortality in Patients With Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) has one of the highest mortality rates among psychiatric disorders. This systematic review and meta‐analysis examined the all‐cause mortality of AN patients compared to the general population using the standardized mortality ratio (SMR).
Eric Tsz‐Him Lai, Benjamin Lai, Corine Sau‐Man Wong, Lai‐Yi Wong, Kin‐Shing Cheng, Pak‐Wing Calvin Cheng, Lo Heidi Ka‐Ying, Gary Tse, Wai‐Chi Chan, Wing‐Chung Chang, Ka‐Fai Chung   +10 more
wiley   +1 more source

Oral Status in Relation to Demographic, Socioeconomic, Medical and Psychosocial Risk Factors Among Outpatients in Addiction Treatment Centers, Stockholm, Sweden

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Objective To investigate oral status in relation to demographic, socioeconomic, medical and psychosocial risk factors among outpatients receiving treatment for Substance Use Disorder (SUD). Methods This cross‐sectional study included 91 outpatients from Stockholm, Sweden. Oral status was assessed using the Decayed, Missing, Filled Teeth (DMFT)
Sonja Rafat, Stefan Borg, Gunnar Edman, Anders Hammarberg, Patricia De Palma   +4 more
wiley   +1 more source

Effect of intrauterine morphine sulfate exposure on cerebellar histomorphological changes in neonatal mice [PDF]

, 2011
Neurotoxic effects of morphine sulfate in adult cerebellar cortex and neonatal cerebral cortex have been studied in animal models. This study was done to determine the neurotoxic effects of prenatal morphine exposure on the histo morphological changes of
Ghafari, S., Golalipour, M.J., Roshandel, D.   +2 more
core  

A guide to chemokines and their receptors [PDF]

, 2018
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G‐protein coupled heptahelical chemokine receptors.
Braun A, Dyer DP, Garton KJ, Gupta SK, Hundelshausen P, Janssens R, Murphy PM, Sozzani S, Speck RF, Suan D, Woollard SM, Zheng Y   +11 more
core   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Nalmefene, an opioid receptor modulator, aggravates atherosclerotic plaque formation in apolipoprotein E knockout mice by enhancing oxidized low-density lipoprotein uptake in macrophages

Biochemistry and Biophysics Reports
Nalmefene, an antagonist of mu- and delta-opioid receptors and a partial agonist of kappa-opioid receptors, has shown promise in reducing alcohol consumption among patients with alcohol dependence.
Mitsuhisa Koga, Koshun Inada, Ayano Yamada, Kana Maruoka, Atsushi Yamauchi   +4 more
doaj   +1 more source

Naloxone in Buprenorphine Overdose: A Life Saving Intervention [PDF]

Journal of Clinical and Diagnostic Research
Buprenorphine acts as a partial agonist at μ-opioid and ORL-1 (nociceptin) receptors, an antagonist at κ-opioid receptors, and an agonist at σ-opioid receptors.
Aviral Ratan Srivastava, Sarbari Swaika, Tanvi Snehal Desai   +2 more
doaj   +1 more source

Delta opioid receptor ‐ kappa opioid receptor heteromer signaling in peripheral nociceptors (659.1)

The FASEB Journal, 2014
We have found that DOR‐KOR heteromers form in peripheral nociceptors (i.e., pain‐sensing neurons) (Berg et al., 2012, Mol Pharmacol 81:264‐272). Here we sought to better understand DOR‐KOR heteromer function in peripheral nociceptors.
Blaine McGuire, Laura Sullivan, Teresa Chavera, William Clarke, Kelly Berg   +4 more
openaire   +1 more source

Evaluation of buprenorphine as optimisation of postoperative analgesia in feral cats undergoing ovariohysterectomy under field conditions

Journal of Small Animal Practice, EarlyView.
Objectives The objective of this prospective, randomised, blinded, observational clinical study was to investigate the effect of subcutaneously administered buprenorphine on postoperative pain in female feral cats undergoing ovariohysterectomy as part of a trap‐neuter‐return programme.
V. Heitzmann, A. Diggelmann, E. Goldinger, A. Schiele   +3 more
wiley   +1 more source