Results 171 to 180 of about 112,812 (208)
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NeuroMolecular Medicine, 2004
Opioid receptors are regulated by multiple mechanisms, which are believed to contribute to the physiological plasticity of the endogenous opioid system in response to natural neuropeptides, as well as clinically relevant opiate drugs. Considerable progress has been made in elucidating molecular and cellular mechanisms of opioid receptor regulation. The
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Opioid receptors are regulated by multiple mechanisms, which are believed to contribute to the physiological plasticity of the endogenous opioid system in response to natural neuropeptides, as well as clinically relevant opiate drugs. Considerable progress has been made in elucidating molecular and cellular mechanisms of opioid receptor regulation. The
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Current Protocols in Pharmacology, 1998
AbstractOpioid receptors mediate the pharmacologic actions of morphine‐like analgesics, a class of drugs that are important clinical agents which are also widely abused socially as a result of their euphorogenic and addictive properties. Cloning of the opioid receptors has confirmed the original postulate that there are only three classes of opioid ...
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AbstractOpioid receptors mediate the pharmacologic actions of morphine‐like analgesics, a class of drugs that are important clinical agents which are also widely abused socially as a result of their euphorogenic and addictive properties. Cloning of the opioid receptors has confirmed the original postulate that there are only three classes of opioid ...
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Pharmaceutisch Weekblad Scientific Edition, 1990
A receptor site is considered to be a transducing factor for effect of the natural ligand. Endorphins and the drugs that mimic their effects (the opiates) are important for analgesia, and consequently the receptor sites involved in actions of opioid drugs are to be considered as relevant to the transmission of pain.
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A receptor site is considered to be a transducing factor for effect of the natural ligand. Endorphins and the drugs that mimic their effects (the opiates) are important for analgesia, and consequently the receptor sites involved in actions of opioid drugs are to be considered as relevant to the transmission of pain.
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1984
Publisher Summary This chapter discusses the heterogeneity and characteristics of opioid receptors. In homogenates of guinea pig brain, [Leu5]enkephalin is more potent in displacing the binding of [3H] [Leu5]enkaphalin than of [3H]naloxone, whereas the converse holds for morphine; in contrast, β-endorphin is equipotent at displacing both tritiated ...
S.J. Paterson +2 more
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Publisher Summary This chapter discusses the heterogeneity and characteristics of opioid receptors. In homogenates of guinea pig brain, [Leu5]enkephalin is more potent in displacing the binding of [3H] [Leu5]enkaphalin than of [3H]naloxone, whereas the converse holds for morphine; in contrast, β-endorphin is equipotent at displacing both tritiated ...
S.J. Paterson +2 more
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Delta Opioid Receptors and Cardioprotection
2017The opioid receptor family, with associated endogenous ligands, has numerous roles throughout the body. Moreover, the delta opioid receptor (DORs) has various integrated roles within the physiological systems, including the cardiovascular system.
Louise E. See Hoe +4 more
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2021
Opioid receptors, beyond their involvement in pain transmission, play a number of relevant physiological roles in the central nervous system and in peripheral organs. Opioid receptors can be considered a crossroads where endogenous opioid peptides and foreign opioids and opiates meet the cell and transmit their messages to another vast array of ...
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Opioid receptors, beyond their involvement in pain transmission, play a number of relevant physiological roles in the central nervous system and in peripheral organs. Opioid receptors can be considered a crossroads where endogenous opioid peptides and foreign opioids and opiates meet the cell and transmit their messages to another vast array of ...
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Multiple opioid receptors [PDF]
Medicinal Research Reviews, 1981 William R. Martin, Edgar T. Iwamoto
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CLASSIFICATION OF OPIOID RECEPTORS
British Medical Bulletin, 1983L.E. Robson +2 more
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Opioid Receptors and Endogenous Opioid Peptides
1980According to Ariens et al. (1964b), the concept of receptors was first proposed by J. N. Langley in 1905 to account for the actions of nicotine and curare at the myoneural junction, and by P. Ehrlich in 1906 to account for specific interactions between antigens and antibodies and for the selectivity of dyes for certain components of living cells.
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