Comportamento de coçar e nocicepção evidenciados após a aplicação facial de endotelina-1: um novo teste, uma nova oportunidade farmacológica [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011O presente trabalho reproduziu o modelo experimental descrito por Shimada e Lamotte, (2008), e o
Gomes, Lenyta Oliveira
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The Hippocampus Is the Place to Be: Opioid Receptors and LTP
Cell Reports, 2019 Nam et al. (2019) genetically modulate the expression of astrocytic μ-opioid receptors to reveal they are necessary for drug-induced conditioned place preference.
Thomas M. Sanderson +3 more
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Molecular Pain, 2017 Background µ-Opioid receptor internalization is considered to be critically linked to antinociceptive tolerance. Although µ-opioid receptor agonists have been administered simultaneously with other drugs to control pain, little information is available ...
Tomohisa Mori +18 more
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Study of opioid receptors [PDF]
, 2016 1 ABSTRACT In this Thesis, we studied properties of μ-, δ-, and κ-opioid receptors in lymphocytes isolated from rat spleen. This splenocytes were exposed to mitogen concanavalin A or opiate morphine and cultivated for 48 hours.
Cechová, Kristína
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The influence of μ-opioid and noradrenaline reuptake inhibition in the modulation of pain responsive neurones in the central amygdala by tapentadol in rats with neuropathy [PDF]
, 2015 Treatments for neuropathic pain are either not fully effective or have problematic side effects. Combinations of drugs are often used. Tapentadol is a newer molecule that produces analgesia in various pain models through two inhibitory mechanisms, namely
Gonçalves, L, Friend, LV, Dickenson, AH
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Buprenorphine-Induced Antinociception Is Mediated by μ-Opioid Receptors and Compromised by Concomitant Activation of Opioid Receptor-Like Receptors [PDF]
, 2003 Buprenorphine is a mixed opioid receptor agonist-antagonist used clinically for maintenance therapy in opiate addicts and pain management. Dose-response curves for buprenorphine-induced antinociception display ceiling effects or are bell shaped, which ...
Takeshima, Hiroshi +21 more
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Nociceptin/orphanin FQ and motor activity: behavioural, biochemical and electrophysiological studies in models of Parkinson’s disease [PDF]
, 2010 Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide which activates the NOP receptor. N/OFQ exerts an inhibitory control on locomotion through inhibition of dopamine (DA) neurons located in the substantia nigra (SN), which degenerate in ...
Viaro, Riccardo
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Frontiers in Psychiatry, 2018 A series of 14β-acyl substituted 17-cyclopropylmethyl-7,8-dihydronoroxymorphinone compounds has been synthesized and evaluated for affinity and efficacy for mu (MOP), kappa (KOP), and delta (DOP) opioid receptors and nociceptin/orphanin FQ peptide (NOP ...
Vinod Kumar +6 more
doaj +1 more source
Local analgesic effect of tramadol is mediated by opioid receptors in late postoperative pain after plantar incision in rats [PDF]
, 2016 José Oswaldo de Oliveira Junior,1 Milena Fernandes de Freitas,2 Carolina Bullara de Andrade,3 Marucia Chacur,2 Hazem Adel Ashmawi1 1Laboratório de Anestesiologia Experimental, Faculdade de Medicina da Universidade de Sã
Bullara de Andrade C +4 more
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The role of δ-opioid receptors in learning and memory underlying the development of addiction [PDF]
, 2015 Opioids are important endogenous ligands that exist in both invertebrates and vertebrates and signal by activation of opioid receptors to produce analgesia and reward or pleasure.
Morgan, Michael +2 more
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