Results 121 to 130 of about 646,259 (330)

Evolution of the C-Type Lectin-Like Receptor Genes of the DECTIN-1 Cluster in the NK Gene Complex

The Scientific World Journal, 2012
Pattern recognition receptors are crucial in initiating and shaping innate and adaptive immune responses and often belong to families of structurally and evolutionarily related proteins.
Susanne Sattler, Hormas Ghadially, Erhard Hofer   +2 more
doaj   +1 more source

Involvement of Pattern Recognition Receptors in Coxsackievirus B Infection of Human Islets [PDF]

, 2013
T1DM is an autoimmune disease in which beta-cells are selectively destroyed by the immune system. As consequence of beta-cell destruction insulin levels decline resulting in elevated blood glucose levels.
Domsgen, Erna
core  

Pattern recognition receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]

, 2019
Pattern Recognition Receptors (PRRs, [89]) (nomenclature as agreed by NC-IUPHAR sub-committee on Pattern Recognition Receptors, [17]) participate in the innate immune response to microbial agents, the stimulation of which leads to activation of ...
Bryant, Clare, Monie, Tom P.
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons

Journal of Neuroinflammation, 2015
An increasing number of studies show that the activation of the innate immune system and inflammatory mechanisms play an important role in the pathogenesis of numerous diseases.
G. Santoni, C. Cardinali, M. Morelli, M. Santoni, M. Nabissi, C. Amantini   +5 more
semanticscholar   +1 more source

Recognition of fungal glucans by pattern recognition receptors [PDF]

, 2003
Glucans are (1→3)-β-D linked polymers of glucose that are major constituents of fungal cells walls. Glucans are known to stimulate innate immunity and they are thought to be fungal pathogen associated molecular patterns.
Brown, G. D., Willment, J. A., Herre, J., Williams, D. L., Taylor, Philip Russel, Rice, R., Gordon, P. R.   +6 more
core  

Activation of plant pattern-recognition receptors by bacteria [PDF]

, 2011
The first active layer of plant innate immunity relies on the recognition by surface receptors of molecules indicative of non-self or modified-self. The activation of pattern-recognition receptors (PRRs) by pathogen-associated molecular patterns (PAMPs ...
Segonzac, Cécile, Zipfel, Cyril, Cécile Segonzac, Cyril Zipfel   +3 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Interaction of Hepatitis C virus proteins with pattern recognition receptors

Virology Journal, 2012
Hepatitis C virus (HCV) is an important human pathogen that causes acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma worldwide. This positive stranded RNA virus is extremely efficient in establishing persistent infection by escaping ...
Imran Muhammad, Waheed Yasir, Manzoor Sobia, Bilal Muhammad, Ashraf Waseem, Ali Muhammad, Ashraf Muhammad   +6 more
doaj   +1 more source

Perception of pathogenic or beneficial bacteria and their evasion of host immunity: pattern recognition receptors in the frontline

Frontiers in Plant Science, 2015
Plants are continuously monitoring the presence of microorganisms to establish an adapted response. Plants commonly use pattern recognition receptors (PRRs) to perceive microbe- or pathogen-associated molecular patterns (MAMPs/PAMPs) which are ...
Lucie Trdá, Freddy Boutrot, Justine Claverie, D. Brulé, S. Dorey, B. Poinssot   +5 more
semanticscholar   +1 more source