Results 251 to 260 of about 93,312 (311)

The pyrogenic mediator prostaglandin E₂ elicits warmth seeking via EP3 receptor-expressing parabrachial neurons: a potential mechanism of chills. [PDF]

J Physiol
Yahiro T, Nakamura Y, Nakamura K.
europepmc   +1 more source

Prostaglandin E receptors and the kidney

American Journal of Physiology-Renal Physiology, 2000
Prostaglandin E2is a major renal cyclooxygenase metabolite of arachidonate and interacts with four G protein-coupled E-prostanoid receptors designated EP1, EP2, EP3, and EP4. Through these receptors, PGE2modulates renal hemodynamics and salt and water excretion. The intrarenal distribution and function of EP receptors have been partially characterized,
M D, Breyer, R M, Breyer
openaire   +3 more sources

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Cyclopentenone prostaglandin receptors

Prostaglandins & Other Lipid Mediators, 2002
Cyclopentenone prostaglandins (PGs), such as 15-deoxy-12,13-didehydro-14,15-didehydro-PGJ2 (15d-delta(12,14)-PDJ2), 12,13-didehydro-PGJ2 (delta12-PGJ2) and PGA2, are actively transported into cells and promote the expression of a variety of genes. The ultimate metabolite of PGD2, 15d-delta(12,14)-PGJ2, specifically binds to a nuclear receptor, the ...
Manabu, Negishi, Hironori, Katoh
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Specific receptors for prostaglandins in airways

Prostaglandins, 1980
The relative bronchomotor activities of prostaglandins (PG) E1, E2, F2 alpha, F2 beta and I2 and of three synthetic E prostaglandin analogues (TR4161, TR4367 and TR4752) were determined on a large number of isolated preparations of guinea-pig trachea and human bronchial muscle. Each prostaglandin was capable of eliciting both contraction and relaxation,
P J, Gardiner, H O, Collier
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Activation of nuclear receptors by prostaglandins

Thrombosis Research, 2003
Deletion of membrane receptors for prostaglandins has revealed their importance in diverse biological systems. Some evidence has accrued to support the contention that they may also ligate nuclear receptors, particularly peroxisomal proliferator activator receptors (PPARs).
Tomomi, Ide, Karine, Egan, L Chastine, Bell-Parikh, Garret A, FitzGerald   +3 more
openaire   +2 more sources

Prostaglandin receptors in rat kidney

Archives of Biochemistry and Biophysics, 1984
The physiological effects of prostaglandins (PGs) are mediated through their interactions with specific binding sites (receptors) on effector cells. Since such receptors potentially regulate the action of PGs on the kidney, the distribution and properties of renal PG receptors in the rat were examined.
C, Limas, C J, Limas
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Thromboxane, Prostaglandin and Leukotriene Receptors

Annual Review of Pharmacology and Toxicology, 1989
Thromboxanes (TX), prostaglandins (PG), and leukotrienes (LT) (eicosa­ noids) are metabolites of the the 20-carbon fatty acid arachidonic acid. Current evidence supports potential pathophysiologic roles for these autocoids in many diseases (1-3).
P V, Halushka, D E, Mais, P R, Mayeux, T A, Morinelli   +3 more
openaire   +2 more sources