Results 171 to 180 of about 35,200 (265)

Resveratrol as a potential natural compound to ameliorate cognitive impairment in aluminum-exposed mice: impacts on behavior, purinergic system, and brain inflammation. [PDF]

Metab Brain Dis
Visentini AE, Reichert KP, Schetinger MRC, Bottari NB, Miron VV, Castro MFV, da Silveira MV, Assmann CE, Schirmann AA, Morsch VMM.   +9 more
europepmc   +1 more source

HIF‐Regulated Pannexin‐1 Channel Drives Luminal ATP Accumulation in Kidney Cysts

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Autosomal dominant polycystic kidney disease causes progressive cyst enlargement in the kidneys, leading to hypoxia and induction of HIF‐1α. Our study identifies HIF‐1α‐dependent transcriptional upregulation of Pannexin1 (PANX1) in the apical membrane of cyst epithelial cells, promoting ATP release into the cyst lumen.
Kathrin Skoczynski, Julia Katharina Scholz, Raluca Ursu, Johannes Schödel, Steffen Grampp, Stephanie Naas, Victoria Lauer, Mario Schiffer, Maike Büttner‐Herold, Bjoern Buchholz, Andre Kraus   +10 more
wiley   +1 more source

Chronic spontaneous urticaria treatments and purinergic signaling: a therapeutic possibility. [PDF]

J Mol Med (Berl)
Fontana M, Simões JLB, de Carvalho Braga G, Fontana M, Filho JCM, Bagatini MD.   +5 more
europepmc   +1 more source

Macrophage‐Fibroblast Crosstalk Shapes Wound Repair Signaling In Vitro

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Intercellular communication between macrophages and fibroblasts is critical for wound healing. Macrophages promoted fibroblast scratch closure through contact‐dependent mechanisms independent of connexins. In contrast, fibroblasts regulated macrophage cytokine secretion via connexin‐43–mediated contact signaling that increased IL10 and paracrine ...
Daniela Enriquez‐Ochoa, Raji R. Nagalla, Yingzi Liu, Christian F. Guerrero‐Juarez, Hamza Atcha, Gordon Chang, Nancy A. Morales, Hannah J. Hooper, Arian D. Cano, Huy Eng Lim, Michael D. Cahalan, Maksim V. Plikus, Wendy F. Liu   +12 more
wiley   +1 more source

Host-directed therapeutic strategies against apicomplexan parasites: targeting purinergic P2 receptors. [PDF]

Purinergic Signal
Chaves MM, Carvalho-Barbosa N, Savio LEB, Coutinho-Silva R.   +3 more
europepmc   +1 more source

Adenosine A2A receptor signaling in neuroinflammation, glial modulation, and mechanisms associated with chronic pain. [PDF]

Purinergic Signal
Barros CA, Rangel JG, de Oliveira Cruz B, De Araújo LP, Galdino G.   +4 more
europepmc   +1 more source

ATP and major affective disorders: the involvement of P2X receptors in pathophysiology. [PDF]

Purinergic Signal
Mattova S, Simko P, Colzi E, Stammova E, Urbanska N, Grigoroiu-Serbanescu M, Coppi E, Kiskova-Simkova T.   +7 more
europepmc   +1 more source

The long march towards testing the adenosine receptor agonism hypothesis for human cerebroprotection: The story of the A₁R/A₃R receptor agonist AST-004. [PDF]

Purinergic Signal
Liston TE, Korinek WS, Jacobson KA, Lechleiter JD.   +3 more
europepmc   +1 more source

Autism Spectrum Disorders and Purinergic Signaling: A Systematic Review of Emerging Insights from Preclinical Studies. [PDF]

J Mol Neurosci
Guha S, Elisha DH, Eshraghi RS, Mittal R, Deth RC, Eshraghi AA.   +5 more
europepmc   +1 more source

Targeting Microglia-Neuron Crosstalk to Regulate Neuronal Excitability: Novel Translational Approaches for Chronic Pain Intervention. [PDF]

Int J Mol Sci
Xu Z, Lv Y, Chen S, Wu Q.
europepmc   +1 more source