Results 161 to 170 of about 35,200 (265)

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 3, Page 362-373, June 2026.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Pannexin-1-mediated ATP signaling as a driver of immune communication and chronic inflammation in HIV infection. [PDF]

Front Immunol
Kaufman EK, Swartz TH.
europepmc   +1 more source

Calcium Buffering in Astrocytes and Its Relevance for Experimental Data Interpretation and Computational Modeling

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Components and properties of Ca2+ buffers in astrocytes, which should be considered for data interpretation and in computational modeling of astrocyte Ca2+ activity. ABSTRACT Astrocytic Ca2+ signaling is essential for maintaining physiological brain function, including the modulation of synaptic transmission, neurovascular coupling, and ion homeostasis.
Kerstin Lenk, Andre Zeug, Franziska E. Müller   +2 more
wiley   +1 more source

Acute effects of a single electroacupuncture session on purinergic signaling and inflammatory markers in patients with chronic nonspecific low back pain: a pilot study. [PDF]

Purinergic Signal
Ecco JC, Ansolin V, Soares AA, Dalagnol AMK, Marafon F, Franscescon F, Bianchini MC, de Resende E Silva DT.   +7 more
europepmc   +1 more source

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros, Laura Barbosa Grossi, Maria Letícia da Silva Campos, Israel Bem‐Hur Netto Cardoso, Antônio Lúcio Teixeira, Aline Silva de Miranda, Eliana Cristina de Brito Toscano   +6 more
wiley   +1 more source

Serum Levels of Glutamatergic (GRIN1) and Purinergic (P2RX1/P2RY2) Receptors in Patients with Fibromyalgia. [PDF]

Int J Mol Sci
Dogan SC, Kaya GC, Tuncbilek Z, Atas M, Tas A.   +4 more
europepmc   +1 more source

The genetic inhibition of GPR17 affects myelination by influencing important players in oligodendrocyte maturation, including purinergic receptors

, 2017
Oligodendrocyte precursor cells (OPCs) are the primary source of myelinating oligodendrocytes in the central nervous system (CNS). Both OPCs and mature oligodendrocytes express purinergic receptors, and for some of them, their expression is restricted to
Fumagalli M, Marangon D, Coppolino GT, Lecca D, Abbracchio MP., Bonfanti E   +5 more
core  

Early Regional Microglial Remodelling in the Hippocampus of the AppNL‐G‐F Alzheimer's Model

Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Microglia undergo profound structural and functional changes during Alzheimer's disease, yet the earliest stages of morphological remodelling that occur prior to amyloid deposition remain poorly defined. Through high‐resolution 3D morphometry in the CA1 region of the hippocampus of AppNL‐G‐F mice, it was found that although microglial numbers and ...
Ryan J. Bevan, Jessica F. Minett, Alice L. Smith, Ana Cardus Figueras, Philip R. Taylor   +4 more
wiley   +1 more source

Purinergic signaling in dengue infection: modulation of P2 receptors as a potential therapeutic strategy. [PDF]

Purinergic Signal
de Melo VC, de Oliveira KI, Kipper M, Bagatini MD, da Silva GB.   +4 more
europepmc   +1 more source

Acute Sleep Deprivation Shifts Substrate Utilization Toward Greater Fat Oxidation During Incremental Exercise in Recreationally Trained Adults

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 6, June 2026.
ABSTRACT Sleep deprivation alters metabolic homeostasis and substrate metabolism, but its effect on fat and carbohydrate utilization during exercise is unclear. This study examined the effects of one night of total and partial sleep deprivation on substrate utilization during a maximal fat oxidation test (MFO) in recreationally trained adults.
Marta del Val‐Manzano, Juan Jesús Montalvo‐Alonso, Paola Gonzalo‐Encabo, David Valadés, Carmen Ferragut, Alberto Pérez‐López   +5 more
wiley   +1 more source