Results 191 to 200 of about 22,494 (202)

Scrutinizing the Therapeutic Promise of Purinergic Receptors Targeting Depression

Neurotoxicity research, 2022
Priyanshi Sikka, T. Behl, Parteek Chandel, Aayush Sehgal, Sukhbir Singh, H. Makeen, M. Albratty, H. A. Alhazmi, A. Meraya   +8 more
semanticscholar   +1 more source

Role of P1 and P2 purinergic receptors during severe in vitro ischemia in the rat CA1 hippocampus and dentate gyrus

2015
The hippocampus is comprised of two distinct subfields that show different responses to hypoxic/ischemic brain injury: the CA1 region is particularly susceptible, whereas the dentate gyrus (DG) is quite resistant. A major resistance of the DG to ischemia in adulthood is probably due to the regenerative capacity of the neural stem cells of the ...
COPPI, ELISABETTA, MARAULA, GIOVANNA, FUSCO, IRENE, PEDATA, FELICITA, PUGLIESE, ANNA MARIA   +4 more
openaire   +1 more source

Synthesis and Characterization of New Ligands for the Purinergic P1 Receptors

2010
Adenosine (Ado) is a naturally occurring nucleoside, involved in the regulation of many physiological and pathophysiological processes through the activation of four specific cell membrane receptors (AA1R, AA2AR, AA2BR, and AA3R), which belong to the superfamily of G protein-coupled receptors. Ado receptors (ARs) are responsible for the wide variety of
openaire   +1 more source

27 Novel Purinergic P1, P2X and P2Y Receptor Signaling Targets in the Human Enteric Nervous System and Glia

Gastroenterology, 2009
Jacqueline E. Wunderlich, Tianhua Ren, Bradley Needleman, Dean J. Mikami, Iveta Grants, Fievos L. Christofi   +5 more
openaire   +1 more source

Purinergic receptors in atherosclerosis: implications for pathophysiology and therapeutic strategies

Journal of physiology and biochemistry
S. Dabravolski, Vasily V Kashtalap, Aleksandra S. Utkina, Gulalek A Babayeva, Anastasia O Maksaeva, V. N. Sukhorukov, Alexander N. Orekhov   +6 more
semanticscholar   +1 more source

Modulating P1 Adenosine Receptors in Disease Progression of SOD1G93A Mutant Mice

Neurochemical Research, 2019
M. Armida, Alessandra Matteucci, A. Pèzzola, Younis Baqi, C. Müller, P. Popoli, R. Potenza   +6 more
semanticscholar   +1 more source

Introduction to the Special Issue on Purinergic Receptors.

Advances in Experimental Medicine and Biology, 2017
G. Burnstock
semanticscholar   +1 more source

Exclusive patent, know-how, process and technology license, including improvements, to develop, use, manufacture, register, market, sell, package, label and sublicense ophthalmic formulations that contain P1,P4-Di(Uridine 5'-Tetraphosphate), based on purinergic receptor agonists, to treat ocular surface diseases in humans, including dry eye.

2000
openaire   +1 more source

Purinergic pathways and their clinical use in the treatment of acute myeloid leukemia

Purinergic Signalling Purinergic Signalling
Huijuan Wang, Yujie Wei, Na Wang
semanticscholar   +1 more source

Microglial purinergic signaling in Alzheimer’s disease

Purinergic Signalling Purinergic Signalling
Shu-Ya Mei, Ning Zhang, Meng-Jing Wang, Pei-Ran Lv, Qi Liu   +4 more
semanticscholar   +1 more source