Results 51 to 60 of about 4,839 (156)
Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
The FEBS Journal, Volume 293, Issue 13, Page 3758-3787, July 2026.The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
The bumpy road of purinergic inhibitors to clinical application in immune-mediated diseases
Neural Regeneration ResearchPurinergic signaling plays important roles throughout the body in the regulation of organ functions during and following the disruption of homeostasis. This is also reflected by the widespread expression of two families of purinergic receptors (P1 and P2)
Matthias T Wyss +2 more
doaj +1 more source
Who Is Who in Adenosine Transport
Frontiers in Pharmacology, 2018 Extracellular adenosine concentrations are regulated by a panel of membrane transporters which, in most cases, mediate its uptake into cells. Adenosine transporters belong to two gene families encoding Equilibrative and Concentrative Nucleoside ...
Marçal Pastor-Anglada +3 more
doaj +1 more source
The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary
Autism Research, Volume 19, Issue 5, May 2026.ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley +1 more source
Modulators of Ion Transport in Nasal Polyps: An Measurement of Short-Circuit Current [PDF]
Clinical and Experimental Otorhinolaryngology, 2008 ObjectivesTo examine possible modulators of the ion transport through the apical membrane of the nasal polyps.MethodsThe study was conducted using the freshly-excised nasal polyps from the patients with chronic sinusitis.
Jun Ho Lee +3 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
NCI-H295R, a human adrenal cortex-derived cell line, expresses purinergic receptors linked to Ca²⁺-mobilization/influx and cortisol secretion. [PDF]
PLoS ONE, 2013 Purinergic receptor expression and involvement in steroidogenesis were examined in NCI-H295R (H295R), a human adrenal cortex cell line which expresses all the key enzymes necessary for steroidogenesis. mRNA/protein for multiple P1 (A(2A) and A(2B)), P2X (
Haruhisa Nishi +2 more
doaj +1 more source
Red Blood Cell Membrane Mechanics Using Discrete Exterior Calculus (DEC) and Optimization
International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 4, April 2026.We present a novel DEC approach for calculating RBC shapes applicable to other cell types and membrane problems. We derive an energy minimization equation that can be solved semi‐implicitly, and a Lie derivative method to control node spacing. This novel work should aid computational modeling in many biological situations.
Keith C. Afas, Daniel Goldman
wiley +1 more source
Frontiers in Cellular Neuroscience, 2019 Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory response, which comprises a rapid initial increase in breathing followed by a slower secondary ...
Robert J. Reklow +13 more
doaj +1 more source