Results 71 to 80 of about 8,556 (198)
Who Is Who in Adenosine Transport
Extracellular adenosine concentrations are regulated by a panel of membrane transporters which, in most cases, mediate its uptake into cells. Adenosine transporters belong to two gene families encoding Equilibrative and Concentrative Nucleoside ...
Marçal Pastor-Anglada +3 more
doaj +1 more source
P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential [PDF]
P2Y receptors for extracellular nucleotides are coupled to activation of a variety of G proteins and stimulate diverse intracellular signaling pathways that regulate functions of cell types that comprise the central nervous system (CNS).
Erb, Laurie +3 more
core +1 more source
Development of the neurohypophysis: A major neuroendocrine interface
Abstract The neurohypophysis is a major central neuroendocrine interface regulating reproductive functions and water homeostasis. Distinct neurovascular cell types interact via evolutionarily conserved signaling molecules in the developing neurohypophysis, providing a model system for studying principles in neuroendocrine interface morphogenesis.
Athul R. Ramesh +5 more
wiley +1 more source
In vitro functional properties of the rat bladder regenerated by the bladder acellular matrix graft. [PDF]
PurposeTo assess the response of rat urinary bladder regenerated by the homologous bladder acellular matrix graft (BAMG) to in vitro electrical and pharmacologic stimuli.Materials and methodsIn Sprague-Dawley rats, partial cystectomy (>50%) was ...
Dahiya, R +5 more
core +1 more source
The E-NTPDase Family of Ectonucleotidases: Structure Function Relationships and Pathophysiological Significance [PDF]
Ectonucleotidases are ectoenzymes that hydrolyze extracellular nucleotides to the respective nucleosides. Within the past decade, ectonucleotidases belonging to several enzyme families have been discovered, cloned and characterized.
Robson, Simon Christopher +2 more
core +1 more source
Recurrent pregnancy loss (RPL), defined as more than two consecutive miscarriages before 20 weeks of gestation, affects 1%–5% of reproductive‐aged women, with nearly half of the cases remaining idiopathic. Using ethanol‐induced endometrial injury in rats to simulate RPL, we demonstrated that mesenchymal stem cells (MSCs) exert therapeutic effects ...
Yunguo Lei +8 more
wiley +1 more source
Modulators of Ion Transport in Nasal Polyps: An Measurement of Short-Circuit Current [PDF]
ObjectivesTo examine possible modulators of the ion transport through the apical membrane of the nasal polyps.MethodsThe study was conducted using the freshly-excised nasal polyps from the patients with chronic sinusitis.
Jun Ho Lee +3 more
doaj +1 more source
Macrophages in wound healing: activation and plasticity. [PDF]
Macrophages are critically involved in wound healing, from dampening inflammation to clearing cell debris and coordinating tissue repair. Within the wound, the complexity of macrophage function is increasingly recognized, with adverse outcomes when ...
Kim, Sang Yong, Nair, Meera G
core
Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release [PDF]
Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in ...
Arnett, T R +5 more
core +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source

