Results 91 to 100 of about 5,101 (183)

Nanobody-Based Biologics for Modulating Purinergic Signaling in Inflammation and Immunity

Frontiers in Pharmacology, 2018
Adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD+) are released as danger signals from cells during infection and sterile inflammation.
Stephan Menzel, Nicole Schwarz, Friedrich Haag, Friedrich Koch-Nolte   +3 more
doaj   +1 more source

Uridine Adenosine Tetraphosphate-Induced Coronary Relaxation Is Blunted in Swine With Pressure Overload: A Role for Vasoconstrictor Prostanoids

Frontiers in Pharmacology, 2018
Plasma levels of the vasoactive substance uridine adenosine tetraphosphate (Up4A) are elevated in hypertensive patients and Up4A-induced vascular contraction is exacerbated in various arteries isolated from hypertensive animals, suggesting a potential ...
Zhichao Zhou, Zhichao Zhou, Zhichao Zhou, Inge M. Lankhuizen, Inge M. Lankhuizen, Heleen M. van Beusekom, Heleen M. van Beusekom, Caroline Cheng, Caroline Cheng, Caroline Cheng, Dirk J. Duncker, Dirk J. Duncker, Daphne Merkus, Daphne Merkus   +13 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors

, 2011
The first demonstrations in the early seventies that adenosine had marked effects in the cerebral cortex, which were independent of its role in intermediary metabolism and could be antagonised by methylxanthines, were followed by the observations that ...
R. Volpini, LAMBERTUCCI, Catia, MARUCCI, Gabriella, DAL BEN, DIEGO, D. Dal Ben, CRISTALLI, Gloria, M. Buccioni, VOLPINI, Rosaria, BUCCIONI, Michela, G. Marucci, G. Cristalli, C. Lambertucci   +11 more
core   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Membrane compartments and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters

, 2009
Receptors should be properly analysed in view of the microenvironment in which they are embedded. Therefore, the concept of 'receptosome' was formulated to the complex interactions taking place between receptors and other proteins at the plasma membrane ...
D'Ambrosi, Nadia, Volonté, Cinzia
core   +1 more source

Synergy between purinergic receptors and nerve growth factor (NGF) in the differentiation and proliferation of neural stem cells

, 2013
Os receptores purinérgicos são divididos em receptores P1 e P2 de acordo com o seu agonista endógeno, os receptores metabotrópicos P1 são ativados por adenosina, enquanto os metabotrópicos P2Y e ionotrópicos P2X são estimulados através do ATP e outros ...
Rodrigo La Banca de Oliveira, Oliveira, Rodrigo La Banca de   +1 more
core   +1 more source

Purinergic enzymes on extracellular vesicles: immune modulation on the go

Frontiers in Immunology
An increase in the extracellular concentration of ATP as a consequence of cellular stress or cell death results in the activation of immune cells. To prevent inflammation, extracellular ATP is rapidly metabolized to adenosine, which deploys an anti ...
Riekje Winzer, Du Hanh Nguyen, Felix Schoppmeier, Felix Schoppmeier, Filippo Cortesi, Filippo Cortesi, Nicola Gagliani, Nicola Gagliani, Eva Tolosa   +8 more
doaj   +1 more source

Astrocytic Receptor Systems of the Basal Ganglia

Receptors
Astrocytes are increasingly recognized as active participants of synaptic communication, yet their role in the basal ganglia circuitry remains poorly defined.
Aleksandar Tushevski, Linus Happe, Elena Stocco, Raffaele De Caro, Veronica Macchi, Andrea Porzionato, Aron Emmi   +6 more
doaj   +1 more source

Antidipsogenic effects of central adenosine-5'-triphosphate

Brazilian Journal of Medical and Biological Research, 2009
Besides other physiological functions, adenosine-5'-triphosphate (ATP) is also a neurotransmitter that acts on purinergic receptors. In spite of the presence of purinergic receptors in forebrain areas involved with fluid-electrolyte balance, the effect ...
D.R.G. de Faria, J.S. Santana, J.V. Menani, P.M. de Paula   +3 more
doaj