Results 101 to 110 of about 681,545 (189)

PET imaging of purinergic receptors

, 2020
Over the recent years, interest in the purinergic signaling system has sparked in the field of positron emission tomography (PET). Purinergic receptors play key roles in physiological and pathological processes, although the exact role in these processes
Windhorst, Albert D., Vugts, Danielle J., Janssen, Bieneke   +2 more
core   +1 more source

Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors. [PDF]

, 2013
Recent investigations have revealed that the genetic deletion of P2X7 receptors (P2rx7) results in an antidepressant phenotype in mice. However, the link between the deficiency of P2rx7 and changes in behavior has not yet been explored.
Zsilla Gabriella, Csölle Cecília, Csölle, Cecília, Illes Peter, Flóra Gölöncsér, Gabriella Zsilla, Mária Baranyi, Sperlágh, Beáta, Baranyi, Mária, Kittel Ágnes, Peter Illes, Baranyi Mária, Beáta Sperlágh, Vizi E. Szilveszter, E Sylvester Vizi, Zsilla, Gabriella, Papp Edit, Gölöncsér Flóra, Illés, Péter, Gölöncsér, Flóra, E. Sylvester Vizi, Sperlágh Beáta, Illes P, Vizi, E. Szilveszter, Papp, Edit, Edit Papp, Kittel, Ágnes, Agnes Kittel, Cecilia Csölle, Vizi E. Sylvester   +29 more
core   +2 more sources

Nanobody-Based Biologics for Modulating Purinergic Signaling in Inflammation and Immunity

Frontiers in Pharmacology, 2018
Adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD+) are released as danger signals from cells during infection and sterile inflammation.
Stephan Menzel, Nicole Schwarz, Friedrich Haag, Friedrich Koch-Nolte   +3 more
doaj   +1 more source

Uridine Adenosine Tetraphosphate-Induced Coronary Relaxation Is Blunted in Swine With Pressure Overload: A Role for Vasoconstrictor Prostanoids

Frontiers in Pharmacology, 2018
Plasma levels of the vasoactive substance uridine adenosine tetraphosphate (Up4A) are elevated in hypertensive patients and Up4A-induced vascular contraction is exacerbated in various arteries isolated from hypertensive animals, suggesting a potential ...
Zhichao Zhou, Zhichao Zhou, Zhichao Zhou, Inge M. Lankhuizen, Inge M. Lankhuizen, Heleen M. van Beusekom, Heleen M. van Beusekom, Caroline Cheng, Caroline Cheng, Caroline Cheng, Dirk J. Duncker, Dirk J. Duncker, Daphne Merkus, Daphne Merkus   +13 more
doaj   +1 more source

Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. [PDF]

, 2000
Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed individually in Xenopus oocytes and studied under ...
B. F. King, Burnstock, G., Wildman, Scott S.P., Townsend-Nicholson, A., Spyer, K. M., King, B F, A. Townsend-Nicholson, Thomas, T., G. Burnstock, Wildman, S. S., Thomas, T, King, B. F., Townsend-Nicholson, A, Burnstock, G, S. S. Wildman, Spyer, K M, T. Thomas, K. M. Spyer   +17 more
core   +1 more source

New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders [PDF]

, 2007
Ionotropic P2X and metabotropic P2Y purinergic receptors are expressed in the central nervous system and participate in the synaptic process particularly associated with acetylcholine, GABA, and glutamate neurotransmission. As a result of activation, the
Trujillo, Cleber Augusto, Gomes, Katia das Neves, Katia N. Gomes, Cleber A. Trujillo, Henning Ulrich, Resende, Rodrigo Ribeiro, Lopes, Camila Galvão, Katia K. Yuahasi, Ulrich, Henning, Rodrigo R. Resende, Paromita Majumder, Luiz R. G. Britto, Majumder, Paromita, Camila G. Lopes, Britto, Luiz Roberto Giorgetti de, Yuahasi, Katia Kioko [UNIFESP]   +15 more
core   +1 more source

Purinergic enzymes on extracellular vesicles: immune modulation on the go

Frontiers in Immunology
An increase in the extracellular concentration of ATP as a consequence of cellular stress or cell death results in the activation of immune cells. To prevent inflammation, extracellular ATP is rapidly metabolized to adenosine, which deploys an anti ...
Riekje Winzer, Du Hanh Nguyen, Felix Schoppmeier, Felix Schoppmeier, Filippo Cortesi, Filippo Cortesi, Nicola Gagliani, Nicola Gagliani, Eva Tolosa   +8 more
doaj   +1 more source

Astrocytic Receptor Systems of the Basal Ganglia

Receptors
Astrocytes are increasingly recognized as active participants of synaptic communication, yet their role in the basal ganglia circuitry remains poorly defined.
Aleksandar Tushevski, Linus Happe, Elena Stocco, Raffaele De Caro, Veronica Macchi, Andrea Porzionato, Aron Emmi   +6 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Antidipsogenic effects of central adenosine-5'-triphosphate

Brazilian Journal of Medical and Biological Research, 2009
Besides other physiological functions, adenosine-5'-triphosphate (ATP) is also a neurotransmitter that acts on purinergic receptors. In spite of the presence of purinergic receptors in forebrain areas involved with fluid-electrolyte balance, the effect ...
D.R.G. de Faria, J.S. Santana, J.V. Menani, P.M. de Paula   +3 more
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