Results 121 to 130 of about 4,839 (156)

Extracellular Vesicles and Purinergic Signaling in Alzheimer's Disease-Joining Forces for Novel Therapeutic Approach. [PDF]

Brain Sci
Lewandowska J, Majewski J, Roszek K.
europepmc   +1 more source

Medial Olivocochlear Efferent Modulation of Cochlear Micromechanics Requires P2X4 Receptor in Outer Hair Cells. [PDF]

J Neurosci
Riffault C, Condamine S, Cerutti A, Bouleau Y, Boué-Grabot E, Dulon D.   +5 more
europepmc   +1 more source

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Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors

Glia, 2012
AbstractMicroglia are sensitive to environmental changes and are immediately transformed into several phenotypes. For such dynamic “modal shifts”, purinergic receptors have central roles. When microglia sense ATP/ADP leaked from injured cells by P2Y12 receptors, they are transformed into a moving phenotype, showing process extension and migration ...
Schuichi, Koizumi, Keiko, Ohsawa, Kazuhide, Inoue, Shinichi, Kohsaka   +3 more
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P1 and P2 purinergic receptor signal transduction in rat type II pneumocytes

Journal of Applied Physiology, 1989
Extracellular ATP is a potent agonist of surfactant phosphatidylcholine (PC) exocytosis from type II pneumocytes in culture. We studied P1 and P2 receptor signal transduction in type II pneumocytes. The EC50 for ATP on PC exocytosis was 10(-6) M, whereas the EC50 for ADP, AMP, adenosine, and the nonmetabolizable ATP analogue alpha,beta-methylene ATP ...
D, Warburton, S, Buckley, L, Cosico
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Genistein, an Inhibitor of Protein Tyrosine Kinase, Is Also a Competitive Antagonist for P1-Purinergic (Adenosine) Receptor in FRTL-5 Thyroid Cells

Biochemical and Biophysical Research Communications, 1994
Genistein, a potent inhibitor for protein tyrosine kinase, remarkably inhibited the stimulatory action of N6-(L-2-phenylisopropyl)adenosine (PIA), an A1-adenosine receptor agonist, on thyrotropin (TSH)-induced phospholipase C activation in FRTL-5 thyroid cells.
F, Okajima, M, Akbar, M, Abdul Majid, K, Sho, H, Tomura, Y, Kondo   +5 more
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On the purinergic system in rat duodenum : existence of P₁and P₂receptors on the smooth muscle

Archives Internationales de Physiologie et de Biochimie, 1990
In rat duodenum, in vitro, in the presence of atropine and guanethidine, ATP administration caused a tetrodotoxin-insensitive relaxation followed by a rebound contraction. A similar response was obtained also after electrical field stimulation (EFS) of non-adrenergic, non-cholinergic (NANC) nerves.
A, Postorino, R, Serio, F, Mulè
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Antihypertensive effects of the Vitis vinifera grape skin (ACH09) extract consumption elicited by functional improvement of P1 (A1) and P2 (P2X1) purinergic receptors in diabetic and hypertensive rats

PharmaNutrition, 2019
Abstract Cross-talk between hypertension and diabetes associated with red wine consumption triggering cardioprotective and antihypertensive effects have been well established; nevertheless, the role of isolated total polyphenols from extracts of Vitis vinifera grape skin (ACH09) and the possible correlation with cardiovascular functionality mediated ...
Guilherme Henrique Souza Bomfim, Diego Castro Musial, Regiane Miranda-Ferreira, Sthefani Rodrigues Nascimento, Aron Jurkiewicz, Neide Hyppolito Jurkiewicz, Roberto Soares de Moura   +6 more
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P1-/P2-purinergic receptors on cultured rabbit retinal Müller cells.

Japanese journal of ophthalmology, 1998
Adenosine 5'-triphosphate (ATP) and its metabolic products function as neurotransmitters or neuromodulators under the control of P1/P2-purinergic receptors. To determine the presence of these receptors on retinal Müller cells, spectrofluorometry was carried out on intracellular calcium mobilization, using Fura-2 images.
Y, Liu, M, Wakakura
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Role of P1 and P2 purinergic receptors in the dentate gyrus during in vitro ischemia

2015
The hippocampus is comprised of two distinct subfields that show different responses to hypoxic/ischemic brain injury: the CA1 region is particularly susceptible, whereas the dentate gyrus (DG) is quite resistant. A major resistance of the DG to ischemia in adulthood is probably due to the regenerative capacity of the neural stem cells of the ...
PUGLIESE, ANNA MARIA, MARAULA, GIOVANNA, LANA, DANIELE, FUSCO, IRENE, MELLO, TOMMASO, Galli, A, COPPI, ELISABETTA, PEDATA, FELICITA   +7 more
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Role of P1 and P2 purinergic receptors during severe in vitro ischemia in the rat CA1 hippocampus and dentate gyrus

2015
The hippocampus is comprised of two distinct subfields that show different responses to hypoxic/ischemic brain injury: the CA1 region is particularly susceptible, whereas the dentate gyrus (DG) is quite resistant. A major resistance of the DG to ischemia in adulthood is probably due to the regenerative capacity of the neural stem cells of the ...
COPPI, ELISABETTA, MARAULA, GIOVANNA, FUSCO, IRENE, PEDATA, FELICITA, PUGLIESE, ANNA MARIA   +4 more
openaire   +1 more source