Results 171 to 180 of about 101,003 (237)

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

Photochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina, Anish Raju Amara, Rafay Abu, Bryan Q. Spring   +3 more
wiley   +1 more source

Retinoic Acid (RA): A Critical Immunoregulatory Molecule in Asthma and Allergies. [PDF]

Immun Inflamm Dis
Lotfi R.
europepmc   +1 more source

Role of vitamins in the development and treatment of osteoporosis (Review). [PDF]

Int J Mol Med
Jiang M, Li G, Yang K, Tao L.
europepmc   +1 more source

Hydroxysteroid 17β‐dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high‐fat diet obese mice

Experimental Physiology, EarlyView.
Abstract Hydroxysteroid 17β‐dehydrogenase 13 (HSD17B13) loss‐of‐function gene variants are associated with a decreased risk of metabolic dysfunction‐associated steatotic liver disease (MASLD). Our RNA‐seq analysis of steatotic liver from obese mice ± fenretinide treatment identified major beneficial effects of fenretinide on expression of hepatic genes
Shehroz Mahmood, Nicola Morrice, Dawn Thompson, Sara Milanizadeh, Sophie Wilson, Philip D. Whitfield, George D. Mcilroy, Justin J. Rochford, Nimesh Mody   +8 more
wiley   +1 more source

Unveiling the Mechanism of Retinoic Acid Therapy for Cutaneous Warts: Insights from Multi-Omics Integration. [PDF]

Clin Cosmet Investig Dermatol
Dong ZY, He MJ, Hu Y, Wang F, Ran DL, Fu DS, He Q, Yang RP, Zhang JA.   +8 more
europepmc   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, EarlyView.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

Cancer treatment and survivorship statistics, 2025

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract The number of people living with a history of cancer in the United States continues to rise because of the growth and aging of the population as well as improved survival through advances in early detection and treatment. To assist the public health community serve the needs of these survivors, the American Cancer Society and the National ...
Nikita Sandeep Wagle, Leticia Nogueira, Theresa P. Devasia, Angela B. Mariotto, K. Robin Yabroff, Farhad Islami, Ahmedin Jemal, Rick Alteri, Patricia A. Ganz, Rebecca L. Siegel   +9 more
wiley   +1 more source

Mesenchymal retinoic acid signaling is required for normal diaphragm development in mice. [PDF]

FASEB J
Garcia Rivas JF, Applin NHM, Albrechtsen JFP, Ghazanfari A, Doschak M, Clugston RD.   +5 more
europepmc   +1 more source

Endogenous Retroelement Activation is Implicated in Interferon‐α Production and Anti–Cyclic Citrullinated Peptide Autoantibody Generation in Early Rheumatoid Arthritis

Arthritis &Rheumatology, Volume 77, Issue 6, Page 646-657, June 2025.
Objective Endogenous retroelements (EREs) stimulate type 1 interferon (IFN‐I) production but have not been explored as potential interferonogenic triggers in rheumatoid arthritis (RA). We investigated ERE expression in early RA (eRA), a period in which IFN‐I levels are increased.
Faye A. H. Cooles, Gemma Vidal Pedrola, Najib Naamane, Arthur G. Pratt, Ben Barron‐Millar, Amy E. Anderson, Catharien M. U. Hilkens, John Casement, Vincent Bondet, Darragh Duffy, Fan Zhang, Ruchi Shukla, John D. Isaacs   +12 more
wiley   +1 more source