Results 171 to 180 of about 57,506 (257)

Genomic Crosstalk Between Nuclear Receptors in Hormone-dependent Cancers.

Endocrinology
Campbell MJ.
europepmc   +1 more source

Phytochemicals Prime RIG-I Signaling and Th1-Leaning Responses in Human Monocyte-Derived Dendritic Cells. [PDF]

Nutrients
Ohki K, Iwasawa T, Kato K.
europepmc   +1 more source

Beyond olfaction: New insights into human odorant binding proteins

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Until today, the exact function of mammalian odorant binding proteins (OBPs) remains a topic of debate. Although their main established function lacks direct evidence in human olfaction, OBPs are traditionally believed to act as odorant transporters in the olfactory sense. Now, available RNA‐seq and proteomics data identified the expression of
Mifen Chen, Soufyan Lakbir, Mihyeon Jeon, Vojta Mazur, Sanne Abeln, Halima Mouhib   +5 more
wiley   +1 more source

Single-cell transcriptomics reveals probiotic reversal of neonatal morphine-induced gene disruptions underlying adolescent pain hypersensitivity. [PDF]

Commun Biol
Tao J, Antoine D, Jalodia R, Valdes E, Boyles SM, Hulme W, Roy S.   +6 more
europepmc   +1 more source

Antitumor Activity of All-Trans Retinoic Acid and Curcumin-Loaded BSA Nanoparticles Against U87 Glioblastoma Cells. [PDF]

Life (Basel)
Sonmez C, Baltacioglu A, Coskun J, Demirbolat GM, Gok O, Ozpinar A.   +5 more
europepmc   +1 more source

Keratinocyte‐Associated Biomarkers Reveal Pathogenic Mechanisms in Acne

FASEB BioAdvances, Volume 8, Issue 2, February 2026.
The study workflow integrates scRNA‐seq and bulk RNA‐seq data to characterize acne pathogenesis. Step 1 identifies expanded keratinocyte populations using single‐cell analysis. Step 2 filters candidate genes via WGCNA and differential expression integration.
Sini Cai, Yinjing Lin, Heng Xie, Xian Ao, Qiwei Liu, Lining Huang   +5 more
wiley   +1 more source

Effects of Bisphenol A and Retinoic Acid Exposure on Neuron and Brain Formation: A Study in Human Induced Pluripotent Stem Cells and Zebrafish Embryos. [PDF]

Environ Health Perspect
Nishie T, Taya T, Omori S, Ueno K, Okamoto Y, Higaki S, Oka M, Mitsuishi Y, Tanaka T, Nakamoto M, Kawahara H, Teraguchi N, Kotaka T, Sawabe M, Takahashi M, Kitaike S, Wada M, Iida K, Yamashita A, Jinno H, Ichimura A, Tooyama I, Sakai N, Hibi M, Hirasawa A, Takada T.   +25 more
europepmc   +1 more source

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man, Zhongyu Cai, Pramath Doddaballapur, Nicole Guerrera, Alexandria Regan, Liqin Lin, Erica Schwarz, Aurelien Justet, Nebal S. Abu Hussein, Jack Di Palo, Cristina Cavinato, Micha Sam B. Raredon, Paul M. Heerdt, Inderjit Singh, Xiting Yan, Min‐Jong Kang, Danielle R. Bruns, Patty J. Lee, George Tellides, Jay D. Humphrey, Naftali Kaminski, Abhay B. Ramachandra, Edward P. Manning   +22 more
wiley   +1 more source

Alginate formulations with high loads of zebularine and retinoic acid promote tissue growth and innervation and induce extensive epigenetic repatterning. [PDF]

Sci Rep
Słonimska P, Baczyński-Keller J, Płatek R, Deptuła M, Dzierżyńska M, Sawicka J, Król O, Sosnowski P, Koczkowska M, Kostecka A, Crossman DK, Crowley MR, Sass P, Smoleński RT, Skowron PM, Piotrowski A, Pikuła M, Rodziewicz-Motowidło S, Sachadyn P.   +18 more
europepmc   +1 more source

Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK‐ULK1‐Mediated Mitochondrial Quality Control

Aging Cell, Volume 25, Issue 2, February 2026.
Dietary protein restriction protects the aging heart in the context of obesity by limiting mitochondrial DNA leakage and suppressing cGAS–STING‐driven inflammation. Through AMPK–ULK1‐dependent mitophagy, protein restriction restores mitochondrial quality control, reduces cardiac remodeling, and preserves metabolic homeostasis during obesity‐associated ...
Wagner S. Dantas, Elizabeth R. M. Zunica, Elizabeth C. Heintz, Charles L. Hoppel, Cristal M. Hill, Christopher D. Morrison, Christopher L. Axelrod, Gangarao Davuluri, John P. Kirwan   +8 more
wiley   +1 more source