Results 251 to 260 of about 99,708 (290)

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

The role of CXCL16 in atherosclerosis: from mechanisms to therapy. [PDF]

Front Immunol
Liu Y, Tian X, Jia C, Cheng X, Cui C, Li C, Yang S.   +6 more
europepmc   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

The role of an anti-inflammatory molecule AIM/CD5L in gut ischemia/reperfusion injury of male mice. [PDF]

Mol Med
Hollis R, Ma G, Jha A, Tenet M, Kato T, Aziz M, Wang P.   +6 more
europepmc   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Dysfunction of the ABCA1 and ABCG1 Transporters and Their Impact on HDL Metabolism. [PDF]

Antioxidants (Basel)
Laguna-Maldonado KD, Uribe-Ramírez D, Vázquez-Carrada M, Matuz-Mares D, Vilchis-Landeros MM.   +4 more
europepmc   +1 more source

In-silico study on biomolecules derived from Cissus quadrangularis towards anti-inflammation. [PDF]

J Genet Eng Biotechnol
Farjana HN, Valiathan GM, Mohanasatheesh S.   +2 more
europepmc   +1 more source

Structure and multiple functions of von Willebrand factor. [PDF]

Haematologica
Haberichter SL, O'Donnell JS.
europepmc   +1 more source

Macrophage subtypes and pathways in autoimmune interstitial lung diseases: potential therapeutic targets. [PDF]

Front Immunol
Tyagi R, Kant S.
europepmc   +1 more source

Anti-JNK2 peptide–siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice [PDF]

, 2018
Akk, Antonina, Bacon, John, Hou, Kirk K, Miller, Mark J, Palekar, Rohun U, Pan, Hua, Pham, Christine T.N, Schlesinger, Paul H, Springer, Luke E, Wickline, Samuel A, Yan, Huimin, Yang, Lihua   +11 more
core   +1 more source