Results 51 to 60 of about 99,708 (290)

Physiological and pathogenic role of scavenger receptors in humans

Медицинская иммунология, 2020
The scavenger receptors (SRs)) include > 30 different molecules structurally classified into 11 classes (A to L). They are expressed mostly on stromal macrophages, and their expression may be augmented in direct dependence with concentrations of their
E. Yu. Gusev, N. V. Zotova, Yu. A. Zhuravleva, V. A. Chereshnev   +3 more
doaj   +1 more source

Scavenger Receptors in Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2006
Atherosclerotic vascular disease arises as a consequence of the deposition and retention of serum lipoproteins in the artery wall. Macrophages in lesions have been shown to express ≥6 structurally different scavenger receptors for uptake of modified forms of low-density lipoproteins (LDLs) that promote the cellular accumulation of cholesterol.
Kathryn J, Moore, Mason W, Freeman
openaire   +2 more sources

Low CD36 and LOX-1 Levels and CD36 Gene Subexpression Are Associated with Metabolic Dysregulation in Older Individuals with Abdominal Obesity

Journal of Diabetes Research, 2016
Background. Obesity study in the context of scavenger receptors has been linked to atherosclerosis. CD36 and LOX-1 are important, since they have been associated with atherogenic and metabolic disease but not fat redistribution.
Perla-Monserrat Madrigal-Ruíz, Rosa-Elena Navarro-Hernández, Sandra-Luz Ruíz-Quezada, Fernanda-Isadora Corona-Meraz, Mónica Vázquez-Del Mercado, Eduardo Gómez-Bañuelos, Jorge Castro-Albarran, Flavio Sandoval-García, Luis-Javier Flores-Alvarado, Beatriz-Teresita Martín-Marquez   +9 more
doaj   +1 more source

Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes

Frontiers in Immunology, 2020
Heat shock proteins (HSP) are a highly abundant class of molecular chaperones that can be released into the extracellular milieu and influence the immune response. HSP release can occur when cells undergo necrosis and exude their contents.
Ayesha Murshid, Thiago J. Borges, Thiago J. Borges, Cristina Bonorino, Cristina Bonorino, Benjamin J. Lang, Stuart K. Calderwood   +6 more
doaj   +1 more source

High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation [PDF]

, 2018
Recent evidence suggests that oxidative stress can play a role in the pathogenesis and the progression of prostate cancer (PCa). Reactive oxygen species (ROS) generation is higher in PCa cells compared to normal prostate epithelial cells and this ...
Botta, Margherita, Calabresi, Laura, Ferri, Nicola, Franceschini, Guido, Giorgio, Eleonora, Gomaraschi, Monica, Macchi, Chiara, Magni, Paolo, Ruscica, Massimiliano   +8 more
core   +2 more sources

The evolution of the class A scavenger receptors

BMC Evolutionary Biology, 2012
Background The class A scavenger receptors are a subclass of a diverse family of proteins defined based on their ability to bind modified lipoproteins. The 5 members of this family are strikingly variable in their protein structure and function, raising ...
Whelan Fiona J, Meehan Conor J, Golding G Brian, McConkey Brendan J, E Bowdish Dawn M   +4 more
doaj   +1 more source

Giant foam-like macrophages in advanced ovarian cancer

Сибирский онкологический журнал, 2022
Introduction. Ovarian cancer (OC) is the third most common gynecological cancer with the worst prognosis and highest mortality rate. The progression of OC can be accompanied by the detrimental functions of the components of the tumor microenvironment ...
M. A. Rakina, E. O. Kazakova, T. S. Sudaskikh, N. V. Bezgodova, A. B. Villert, L. A. Kolomiets, I. V. Larionova   +6 more
doaj   +1 more source

The hepatoadrenal syndrome: A common yet unrecognized clinical condition [PDF]

, 2005
Objective: Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-
Acton, Ali, Annane, Annane, Baranova, Beishuizen, Borkowski, Calco, Cicognani, Cooper, Darlington, Davies, de la Llera-Moya, Dimopoulou, Eisenberg, Ettinger, Gordon, Hamrahian, Harry, Hinshaw, Jaattela, Kilger, Liu, Liu, Liu, Liu, Loriaux, Marik, Marik, Marik, Marik, Marik, McDonald, Melby, Miyata, Molijn, Molijn, Mookerjee, Paul E. Marik, Rasaratnam, Rivers, Scammell, Singh, Sun, Thomas E. Starzl, Timothy Gayowski, van der Voort, van Leeuwen, Vishnyakova, Yaguchi, Yokoyama, Yokoyama   +51 more
core   +1 more source

Scavenger receptors: a key player in cardiovascular diseases

Biomolecular Concepts, 2012
The scavenger receptor (SR) super family consists of integral membrane glycoproteins that are involved in recognition of polyanionic structures of either endogenous (e.g., oxidized low-density lipoprotein) or exogenous (e.g., bacterial ...
Ashraf Mohammad Z., Sahu Anita
doaj   +1 more source

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.

PLoS Pathogens, 2009
Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish, Kaori Sakamoto, Mi-Jeong Kim, Mariliis Kroos, Subhankar Mukhopadhyay, Cynthia A Leifer, Karl Tryggvason, Siamon Gordon, David G Russell   +8 more
doaj   +1 more source