Results 31 to 40 of about 54,333 (259)

Low CD36 and LOX-1 Levels and CD36 Gene Subexpression Are Associated with Metabolic Dysregulation in Older Individuals with Abdominal Obesity

Journal of Diabetes Research, 2016
Background. Obesity study in the context of scavenger receptors has been linked to atherosclerosis. CD36 and LOX-1 are important, since they have been associated with atherogenic and metabolic disease but not fat redistribution.
Perla-Monserrat Madrigal-Ruíz, Rosa-Elena Navarro-Hernández, Sandra-Luz Ruíz-Quezada, Fernanda-Isadora Corona-Meraz, Mónica Vázquez-Del Mercado, Eduardo Gómez-Bañuelos, Jorge Castro-Albarran, Flavio Sandoval-García, Luis-Javier Flores-Alvarado, Beatriz-Teresita Martín-Marquez   +9 more
doaj   +1 more source

Immunological Outcomes Mediated Upon Binding of Heat Shock Proteins to Scavenger Receptors SCARF1 and LOX-1, and Endocytosis by Mononuclear Phagocytes

Frontiers in Immunology, 2020
Heat shock proteins (HSP) are a highly abundant class of molecular chaperones that can be released into the extracellular milieu and influence the immune response. HSP release can occur when cells undergo necrosis and exude their contents.
Ayesha Murshid, Thiago J. Borges, Thiago J. Borges, Cristina Bonorino, Cristina Bonorino, Benjamin J. Lang, Stuart K. Calderwood   +6 more
doaj   +1 more source

Giant foam-like macrophages in advanced ovarian cancer

Сибирский онкологический журнал, 2022
Introduction. Ovarian cancer (OC) is the third most common gynecological cancer with the worst prognosis and highest mortality rate. The progression of OC can be accompanied by the detrimental functions of the components of the tumor microenvironment ...
M. A. Rakina, E. O. Kazakova, T. S. Sudaskikh, N. V. Bezgodova, A. B. Villert, L. A. Kolomiets, I. V. Larionova   +6 more
doaj   +1 more source

Macrophage Scavenger Receptor Class A [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2000
Abstract—In atherogenesis, elevated plasma levels of low density lipoprotein (LDL) lead to the chronic presence of LDL in the arterial wall. There, LDL is modified (eg, oxidized), and these modified lipoproteins activate endothelial cells, which attract circulating monocytes.
Winther, M.P.J. de, Dijk, K.W. van, Havekes, L.M., Hofker, M.H.   +3 more
openaire   +3 more sources

Scavenger receptors: a key player in cardiovascular diseases

Biomolecular Concepts, 2012
The scavenger receptor (SR) super family consists of integral membrane glycoproteins that are involved in recognition of polyanionic structures of either endogenous (e.g., oxidized low-density lipoprotein) or exogenous (e.g., bacterial ...
Ashraf Mohammad Z., Sahu Anita
doaj   +1 more source

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.

PLoS Pathogens, 2009
Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish, Kaori Sakamoto, Mi-Jeong Kim, Mariliis Kroos, Subhankar Mukhopadhyay, Cynthia A Leifer, Karl Tryggvason, Siamon Gordon, David G Russell   +8 more
doaj   +1 more source

Apoptotic cell recognition receptors and scavenger receptors [PDF]

Immunological Reviews, 2015
SummaryPhosphatidylserine recognition receptors are a highly diverse set of receptors grouped by their ability to recognize the ‘eat‐me’ signal phosphatidylserine on apoptotic cells. Most of the phosphatidylserine recognition receptors dampen inflammation by inducing the production of anti‐inflammatory mediators during the phagocytosis of apoptotic ...
Kristen K, Penberthy, Kodi S, Ravichandran   +1 more
openaire   +2 more sources

Scavenger receptors clear the air [PDF]

Journal of Clinical Investigation, 2007
Inhaled environmental oxidants, such as ozone and particulates, have been variably linked to epithelial injury, inflammation, and perturbations in lung development, growth, and function. Reactions between ozone and lung surface lipids likely account for exposure-related pathophysiologic sequelae. In this issue of the JCI, Dahl et al.
openaire   +2 more sources

Scavenger Receptors in Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2006
Atherosclerotic vascular disease arises as a consequence of the deposition and retention of serum lipoproteins in the artery wall. Macrophages in lesions have been shown to express ≥6 structurally different scavenger receptors for uptake of modified forms of low-density lipoproteins (LDLs) that promote the cellular accumulation of cholesterol.
Kathryn J, Moore, Mason W, Freeman
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source