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Physiological and pathogenic role of scavenger receptors in humans
Медицинская иммунология, 2020 The scavenger receptors (SRs)) include > 30 different molecules structurally classified into 11 classes (A to L). They are expressed mostly on stromal macrophages, and their expression may be augmented in direct dependence with concentrations of their
E. Yu. Gusev +3 more
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The Integration of Positron Emission Tomography With Magnetic Resonance Imaging [PDF]
, 2008 A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET).
Cherry, Simon R. +2 more
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Scavenger Receptors in Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 Atherosclerotic vascular disease arises as a consequence of the deposition and retention of serum lipoproteins in the artery wall. Macrophages in lesions have been shown to express ≥6 structurally different scavenger receptors for uptake of modified forms of low-density lipoproteins (LDLs) that promote the cellular accumulation of cholesterol.
Kathryn J, Moore, Mason W, Freeman
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Journal of Diabetes Research, 2016 Background. Obesity study in the context of scavenger receptors has been linked to atherosclerosis. CD36 and LOX-1 are important, since they have been associated with atherogenic and metabolic disease but not fat redistribution.
Perla-Monserrat Madrigal-Ruíz +9 more
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Frontiers in Immunology, 2020 Heat shock proteins (HSP) are a highly abundant class of molecular chaperones that can be released into the extracellular milieu and influence the immune response. HSP release can occur when cells undergo necrosis and exude their contents.
Ayesha Murshid +6 more
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Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
, 1999 The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT +28 more
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The evolution of the class A scavenger receptors
BMC Evolutionary Biology, 2012 Background The class A scavenger receptors are a subclass of a diverse family of proteins defined based on their ability to bind modified lipoproteins. The 5 members of this family are strikingly variable in their protein structure and function, raising ...
Whelan Fiona J +4 more
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Giant foam-like macrophages in advanced ovarian cancer
Сибирский онкологический журнал, 2022 Introduction. Ovarian cancer (OC) is the third most common gynecological cancer with the worst prognosis and highest mortality rate. The progression of OC can be accompanied by the detrimental functions of the components of the tumor microenvironment ...
M. A. Rakina +6 more
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Scavenger receptors: a key player in cardiovascular diseases
Biomolecular Concepts, 2012 The scavenger receptor (SR) super family consists of integral membrane glycoproteins that are involved in recognition of polyanionic structures of either endogenous (e.g., oxidized low-density lipoprotein) or exogenous (e.g., bacterial ...
Ashraf Mohammad Z., Sahu Anita
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PLoS Pathogens, 2009 Virtually all of the elements of Mycobacterium tuberculosis (Mtb) pathogenesis, including pro-inflammatory cytokine production, granuloma formation, cachexia, and mortality, can be induced by its predominant cell wall glycolipid, trehalose 6,6 ...
Dawn M E Bowdish +8 more
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