Results 11 to 20 of about 620,080 (291)
Scavenger receptors in innate immunity
Current Opinion in Immunology, 2002 Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells.
Peiser, L, Mukhopadhyay, S, Gordon, S
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Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]
, 2004 N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
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Current Biology, 2020 Scavenger receptors (SRs) are a large family of cell-surface receptors that are diverse in their structure and biological function and are divided into different classes. SRs can bind to a range of ligands and enhance the elimination of altered-self or non-self targets.
Ali, Alquraini, Joseph, El Khoury
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Alpha-Fetoprotein Binding Mucin and Scavenger Receptors: An Available Bio-Target for Treating Cancer
Frontiers in Oncology, 2021 Alpha-fetoprotein (AFP) entrance into cancer cells is mediated by AFP receptors (AFPRs) and exerts malignant effects. Therefore, understanding the structure of AFPRs will facilitate the development of rational approaches for vaccine design, drug delivery,
Bo Lin +6 more
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More Than Just a Removal Service: Scavenger Receptors in Leukocyte Trafficking
Frontiers in Immunology, 2018 Scavenger receptors are a highly diverse superfamily of proteins which are grouped by their inherent ability to bind and internalize a wide array of structurally diverse ligands which can be either endogenous or exogenous in nature.
Daniel A. Patten, Shishir Shetty
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Targeting Scavenger Receptors in Inflammatory Disorders and Oxidative Stress
Antioxidants, 2022 Oxidative stress and inflammation cannot be considered as diseases themselves; however, they are major risk factors for the development and progression of the pathogenesis underlying many illnesses, such as cancer, neurological disorders (including ...
Govigerel Bayarsaikhan +3 more
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Loss of Function of Scavenger Receptor SCAV-5 Protects C. elegans Against Pathogenic Bacteria
Frontiers in Cellular and Infection Microbiology, 2021 Scavenger receptors play a critical role in innate immunity by acting as the pattern-recognition receptors. There are six class B scavenger receptors homologs in C. elegans.
Aixiao Luo +5 more
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Scavenger receptors in atherosclerosis [PDF]
Current Opinion in Hematology, 1997 Membership in the broad family of scavenger receptors has grown significantly. Two new scavenger receptor receptors have been cloned (SR-BI and SR-CI) and a previously isolated integral membrane protein (CD36) has been found to possess lipoprotein binding properties that entitle it to be included in the family. The breadth of ligand recognition of this
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Scavenger receptor-BI is a receptor for lipoprotein(a) [PDF]
Journal of Lipid Research, 2013 Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low density lipoprotein (LDL), but lipoprotein(a) [Lp(a)] has not been investigated as a possible ligand. Stable cell lines (HEK293 and HeLa) expressing human SR-BI were incubated with protein- or lipid-
Xiao-Ping Yang +9 more
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The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges
Journal of Lipid Research, 2009 It is now thirty years since the original observation that macrophages take up and degrade modified forms of low density lipoprotein (LDL). Molecular cloning has identified multiple scavenger receptors that can endocytose modified LDL and binding studies
David R. Greaves, Siamon Gordon
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