Results 251 to 260 of about 530,601 (300)

A Zebrafish Galectin-1 Isoform Is Expressed in Skin and Gills and Binds to Bacteria, Bacterial Adhesin Receptors, and Epidermal Mucus Glycans. [PDF]

Int J Mol Sci
Feng C, Abernathy K, Wang S, Zong G, Zmora N, Shupp A, Iqbal M, Wang LX, Vasta GR.   +8 more
europepmc   +1 more source

Myeloid Cell-Derived Thrombospondin-1 Mediates Anti-Metastatic Effects of Histamine Dihydrochloride in B16 Melanoma. [PDF]

Immunotargets Ther
Issdisai N, Kaya M, Hellstrand K, Grauers Wiktorin H, Martner A.   +4 more
europepmc   +1 more source

Modulation of Corticotropin-Releasing Hormone Receptor Expression During In Vitro Keratinocyte Differentiation. [PDF]

Curr Issues Mol Biol
Martins CA, Lesink S, Roux A, Collet G, Daniellou R.   +4 more
europepmc   +1 more source

ATP-related purinergic signaling via P2Y12 contributes to airway epithelial barrier integrity. [PDF]

BMC Mol Cell Biol
Tsuya K, Maruoka S, Okamoto S, Shikano S, Ujike M, Yamada S, Kurosawa Y, Mizumura K, Kozu Y, Gon Y.   +9 more
europepmc   +1 more source

Sigma Receptors and Cocaine Abuse [PDF]

Current Topics in Medicinal Chemistry, 2011
Sigma receptors have been well documented as a protein target for cocaine and have been shown to be involved in the toxic and stimulant actions of cocaine. Strategies to reduce the access of cocaine to sigma receptors have included antisense oligonucleotides to the sigma-1 receptor protein as well as small molecule ligand with affinity for sigma ...
Sanju, Narayanan, Christophe, Mesangeau, Jacques H, Poupaert, Christopher R, McCurdy   +3 more
openaire   +3 more sources

Sigma Receptors in Oncology: Therapeutic and Diagnostic Applications of Sigma Ligands [PDF]

Current Pharmaceutical Design, 2010
Sigma receptors (subtypes sigma-1 and sigma-2) are a unique class of binding sites expressed throughout the mammalian body. The endogenous ligand for these sites has not been identified, but steroid hormones (particularly progesterone), sphingolipid-derived amines and N,N-dimethyltryptamine can bind with fairly high affinity.
Aren, van Waarde, Anna A, Rybczynska, Nisha, Ramakrishnan, Kiichi, Ishiwata, Philip H, Elsinga, Rudi A J O, Dierckx   +5 more
core   +5 more sources

Sigma Receptors and Alcohol Use Disorders [PDF]

, 2016
Although extensive research has focused on understanding the neurobiological mechanisms underlying alcohol addiction, pharmacological treatments for alcohol use disorders are very limited and not always effective. This constraint has encouraged the search for novel pharmacological targets for alcoholism therapy.
Valentina, Sabino, Pietro, Cottone
openaire   +3 more sources

Sigma Receptors and Substance Use Disorders [PDF]

, 2017
Thanks to advances in neuroscience, addiction is now recognized as a chronic brain disease with genetic, developmental, and cultural components. Drugs of abuse, including alcohol, are able to produce significant neuroplastic changes responsible for the profound disturbances shown by drug addicted individuals.
Valentina, Sabino, Callum, Hicks, Pietro, Cottone   +2 more
openaire   +3 more sources