Results 171 to 180 of about 563,890 (226)

Toward precision medicine in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease. [PDF]

ERJ Open Res
Sim S, Shin YS, Park JW, Park HS.
europepmc   +1 more source

Functional toll-like receptor 4 links endotoxin sensing to platelet priming in feline platelets. [PDF]

Front Vet Sci
Li RHL, Shaverdian M, Chen C, Stuhlmann C, Stern JA, Nguyen N.   +5 more
europepmc   +1 more source

12(S)-HETE regulates the expression of IL-6 and IL-10 in cardiomyocytes through two distinct receptors, TXA2R and BLT2. [PDF]

Biochem Biophys Rep
Mori S, Takeda Y, Tomimatsu M, Kametani Y, Yoneda N, Egawa K, Hase H, Tanaka S, Okuda M, Okada Y, Obana M, Fujio Y.   +11 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Thromboxane, Prostaglandin and Leukotriene Receptors

Annual Review of Pharmacology and Toxicology, 1989
Thromboxanes (TX), prostaglandins (PG), and leukotrienes (LT) (eicosa­ noids) are metabolites of the the 20-carbon fatty acid arachidonic acid. Current evidence supports potential pathophysiologic roles for these autocoids in many diseases (1-3).
P V, Halushka, D E, Mais, P R, Mayeux, T A, Morinelli   +3 more
openaire   +3 more sources

Aspects of the thromboxane receptor system

General Pharmacology: The Vascular System, 1995
1. The aim of this review is to establish what is known about the thromboxane (TP) receptor, and to identify where future research is headed. In addition, the impact of the recent advances at the molecular level on resolving pharmacological controversies, such as possible subtypes of the TP receptor, is discussed and what molecular information is known
R A, Armstrong, N H, Wilson
openaire   +2 more sources

Glibenclamide inhibits thromboxane-mediated vasoconstriction by thromboxane receptor blockade

Vascular Pharmacology, 2004
Because sulfonylureas, such as glibenclamide, are used to treat Type 2 diabetes and because this disease is associated with various cardiovascular complications that may be mediated by thromboxane (TX), this study was designed to characterize the role of glibenclamide on TX-mediated contractions in isolated ring segments of bovine coronary arteries and
Sandra L, Pfister, Philip E, Pratt, Joseph, Kurian, William B, Campbell   +3 more
openaire   +2 more sources

Thromboxane synthase inhibitors and receptor antagonists

Cardiovascular Drugs and Therapy, 1992
Platelet activation plays a major role in myocardial infarction and in reocclusion following successful thrombolysis, as corroborated by several clinical studies using aspirin. However, the overall reduction of new vascular complications in patients with symptomatic arterial disease by aspirin was only around 25%.
J, Vermylen, H, Deckmyn
openaire   +2 more sources

Cellular Activation of Thromboxane Receptors^a

Annals of the New York Academy of Sciences, 1994
Thromboxane A2 is an abundant and potent product of arachidonic acid metabolism in human platelets. Its clinical importance is highlighted by the efficacy of aspirin, which, due to its irreversible inhibition of the enzyme PGG/H synthase, selects the anucleate platelet as a particular target for extended duration of action.
B T, Kinsella, D, O'Mahony, J A, Lawson, D, Pratico, G A, Fitzgerald   +4 more
openaire   +2 more sources

Thromboxane receptors in human kidney tissues

Prostaglandins & Other Lipid Mediators, 1999
Thromboxane (TX) A2 effects in the kidneys include contraction of glomerular mesangial cells and intrarenal vascular tissue. A kidney cDNA encoding a TX receptor expressed in rat renal glomeruli and rat renal arterial smooth muscle cells has been reported. However, TXA2 receptors in human kidneys have not been documented.
G P, Brown, R C, Venuto
openaire   +2 more sources

Immunohistochemical localization of thromboxane receptor and thromboxane synthase in rat testis

Endocrinology, 1995
The cellular localization of thromboxane A2 receptor (TXR) and thromboxane synthase (TXS) in rat testes was examined with an antibody against the carboxyl-terminal tail of rat TXR and anti-porcine lung TXS antibody. By light microscopy immunoreactivity for TXR was shown to be present in spermatids, whereas spermatogonia, spermatocytes, and spermatozoa ...
N, Takahashi, K, Takeuchi, T, Abe, K, Murakami, M, Yamaguchi, K, Abe   +5 more
openaire   +3 more sources