Poultry Science, 2021 Dysregulation of the preovulatory surge (PS) leads to lowered egg production. The hypothalamo–pituitary–thyroid (HPT) axis has been shown to influence plasma progesterone levels and follicle ovulation.
Kristen Brady +3 more
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Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland
International Journal of Endocrinology, 2022 Hyperandrogenism causes dysfunction of the hypothalamic–pituitary–gonadal (HPG) axis in reproductive women. In this study, we examined the effects of dihydrotestosterone (DHT) on characteristic changes in rat anterior pituitary gland samples.
Haruhiko Kanasaki +6 more
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Dimerization of the thyrotropin-releasing hormone receptor potentiates hormone-dependent receptor phosphorylation [PDF]
Proceedings of the National Academy of Sciences, 2007 The G protein-coupled thyrotropin (TSH)-releasing hormone (TRH) receptor forms homodimers. Regulated receptor dimerization increases TRH-induced receptor endocytosis. These studies test whether dimerization increases receptor phosphorylation, which could potentiate internalization.
Gyun Jee, Song +2 more
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Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status. [PDF]
PLoS ONE, 2014 Reversing the escalating rate of obesity requires increased knowledge of the molecular mechanisms controlling energy balance. Liver X receptors (LXRs) and thyroid hormone receptors (TRs) are key physiological regulators of energetic metabolism. Analysing
Rym Ghaddab-Zroud +4 more
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Thyrotropin-releasing hormone receptors in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE, 2023 Thyrotropin-releasing hormone (TRH) receptors (provisional nomenclature as recommended by NC-IUPHAR [14]) are activated by the endogenous tripeptide TRH (pGlu-His-ProNH2). TRH and TRH analogues fail to distinguish TRH1 and TRH2 receptors [29]. [3H]TRH (human, mouse, rat) is able to label both TRH1 and TRH2 receptors with Kd values of 13 and 9 nM ...
Rebecca Hills +2 more
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eLife, 2020 Whether leptin acts in the paraventricular nucleus (PVN) to increase sympathetic nerve activity (SNA) is unclear, since PVN leptin receptors (LepR) are sparse.
Zhigang Shi +7 more
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Intrauterine Zn deficiency favors thyrotropin-releasing hormone-increasing effects on thyrotropin serum levels and induces subclinical hypothyroidism in weaned rats [PDF]
, 2017 Individuals who consume a diet deficient in zinc (Zn-deficient) develop alterations in hypothalamic-pituitary-thyroid axis function, i.e., a low metabolic rate and cold insensitivity.
Alcántara-Alonso, Viridiana +3 more
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HYPOTHALAMIC NEUROHORMONES AND IMMUNE RESPONSES
Frontiers in Integrative Neuroscience, 2013 The aim of this review is to provide a comprehensive examination of the current literature describing the neural-immune interactions, with emphasis on the most recent findings of the effects of neurohormones on immune system.
J. Luis eQuintanar, Irene eGuzmán-Soto
doaj +1 more source
Glycosylation in the thyroid gland : vital aspects of glycoprotein function in thyrocyte physiology and thyroid disorders [PDF]
, 2018 The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins.
Ewa Pocheć +2 more
core +1 more source
Large-Scale Combinatorial Deorphanization of Platynereis Neuropeptide GPCRs
Cell Reports, 2015 Neuropeptides, representing the largest class of neuromodulators, commonly signal by G-protein-coupled receptors (GPCRs). While the neuropeptide repertoire of several metazoans has been characterized, many GPCRs are orphans.
Philipp Bauknecht, Gáspár Jékely
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