Results 11 to 20 of about 6,474 (167)
Poultry Science, 2021 Dysregulation of the preovulatory surge (PS) leads to lowered egg production. The hypothalamo–pituitary–thyroid (HPT) axis has been shown to influence plasma progesterone levels and follicle ovulation.
Kristen Brady +3 more
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Cloning and Characterization of the Chicken Thyrotropin-Releasing Hormone Receptor* [PDF]
Endocrinology, 1998 We report on the cloning of the full-length complementary DNA for the chicken TRH receptor. Although the TRH receptor has been cloned from several mammalian species, this is the first report from another vertebrate class. The ligand binding pocket, which is situated in the transmembrane helices of the mouse and rat TRH receptors, is completely ...
Y M, Sun +4 more
openaire +3 more sources
Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland
International Journal of Endocrinology, 2022 Hyperandrogenism causes dysfunction of the hypothalamic–pituitary–gonadal (HPG) axis in reproductive women. In this study, we examined the effects of dihydrotestosterone (DHT) on characteristic changes in rat anterior pituitary gland samples.
Haruhiko Kanasaki +6 more
doaj +1 more source
Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor [PDF]
Frontiers in Endocrinology, 2012 Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system. We found that TAL exhibited lower binding affinities than TRH and lower signaling potency via the inositol-1,4,5 ...
Thirunarayanan, Nanthakumar +2 more
openaire +3 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status. [PDF]
PLoS ONE, 2014 Reversing the escalating rate of obesity requires increased knowledge of the molecular mechanisms controlling energy balance. Liver X receptors (LXRs) and thyroid hormone receptors (TRs) are key physiological regulators of energetic metabolism. Analysing
Rym Ghaddab-Zroud +4 more
doaj +1 more source
eLife, 2020 Whether leptin acts in the paraventricular nucleus (PVN) to increase sympathetic nerve activity (SNA) is unclear, since PVN leptin receptors (LepR) are sparse.
Zhigang Shi +7 more
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Dimerization of the thyrotropin-releasing hormone receptor potentiates hormone-dependent receptor phosphorylation [PDF]
Proceedings of the National Academy of Sciences, 2007 The G protein-coupled thyrotropin (TSH)-releasing hormone (TRH) receptor forms homodimers. Regulated receptor dimerization increases TRH-induced receptor endocytosis. These studies test whether dimerization increases receptor phosphorylation, which could potentiate internalization.
Gyun Jee, Song +2 more
openaire +2 more sources
HYPOTHALAMIC NEUROHORMONES AND IMMUNE RESPONSES
Frontiers in Integrative Neuroscience, 2013 The aim of this review is to provide a comprehensive examination of the current literature describing the neural-immune interactions, with emphasis on the most recent findings of the effects of neurohormones on immune system.
J. Luis eQuintanar, Irene eGuzmán-Soto
doaj +1 more source
Large-Scale Combinatorial Deorphanization of Platynereis Neuropeptide GPCRs
Cell Reports, 2015 Neuropeptides, representing the largest class of neuromodulators, commonly signal by G-protein-coupled receptors (GPCRs). While the neuropeptide repertoire of several metazoans has been characterized, many GPCRs are orphans.
Philipp Bauknecht, Gáspár Jékely
doaj +1 more source