Results 71 to 80 of about 9,959 (228)

Intramuscular pathways of maladaptation in overtraining syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu   +2 more
wiley   +1 more source

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner.

open access: yes, 2013
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre   +7 more
core   +1 more source

Thermal challenge and food intake: Mutual regulatory mechanisms

open access: yesNeural Regeneration Research
Human energy homeostasis principally depends on thermal and food intake regulation mechanisms. In addition to describing the major pathways, brain centers, and their connections which control these functions, this review focuses on (i) interrelations ...
Alán Alpár
doaj   +1 more source

A Prospective Evaluation of Glucagon Stimulation Test Safety in Adults With Chronic Moderate‐to‐Severe Traumatic Brain Injury

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
The glucagon stimulation test demonstrates a favourable safety profile in adults with chronic moderate‐to‐severe traumatic brain injury, with transient, non‐severe adverse effects and no serious complications. ABSTRACT Introduction Growth hormone deficiency (GHD) is a common and clinically significant consequence of moderate‐to‐severe traumatic brain ...
Corey Snyder   +2 more
wiley   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]

open access: yes, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M.   +11 more
core   +1 more source

Taste and Smell Disturbances Associated With Secondary Adrenal Insufficiency: A Case Report

open access: yesJournal of General and Family Medicine, Volume 27, Issue 4, July 2026.
ABSTRACT Background Adrenal insufficiency often presents with nonspecific symptoms, impeding early diagnosis. Taste and smell disturbances are rarely recognized as presenting features. Case Presentation We report the case of a 54‐year‐old man with a 3‐month history of persistent taste and smell disturbances accompanied by fatigue, loss of appetite ...
Takanori Izumi   +8 more
wiley   +1 more source

At the transition from invertebrates to vertebrates a novel GnRH-like peptide emerges in amphioxus

open access: yes, 2014
This work was supported by a grant from the Canadian Natural Sciences and Engineering Council (NSERC).Gonadotropin-releasing hormone (GnRH) is a critical reproductive regulator in vertebrates.
Roch, Graeme   +2 more
core   +1 more source

The role of estrogen receptors (ERs)-Notch pathway in thyroid toxicity induced by Di-2-ethylhexyl phthalate (DEHP) exposure: Population data and in vitro studies

open access: yesEcotoxicology and Environmental Safety
Background: This study aimed to assess the exposure level and risk of Di-2-ethylhexyl Phthalate (DEHP) among adults in Jilin Province, China, clarify the impact of DEHP on human thyroid function, and to explore the role of estrogen receptors (ERs)-Notch ...
Xueting Zhang   +8 more
doaj   +1 more source

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