Microvascular Ultrasonography Vascularity Index as a Rapid and Simplified Assessment Tool for Differentiating Graves’ Disease from Destructive Thyroiditis and Managing Thyrotoxicosis [PDF]
Endocrinology and MetabolismBackground Thyrotoxicosis presents significant diagnostic challenges in distinguishing Graves’ disease (GD) from destruction-induced thyrotoxicosis (DT) using ultrasound imaging.
Han-Sang Baek +3 more
doaj +1 more source
Biochemical and physiological insights into TRH receptor-mediated signaling
Frontiers in Cell and Developmental Biology, 2022 Thyrotropin-releasing hormone (TRH) is an important endocrine agent that regulates the function of cells in the anterior pituitary and the central and peripheral nervous systems.
Radka Trubacova +2 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Grave’s orbitopathy – an approach to clinical evaluation and management
Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2012 Grave’s orbitopathy (GO), is a potentially sight threatening condition which constitutes a major clinical and therapeutic challenge and occurs in about 50% of patients with Grave’s disease with only 3-5% cases posing threat to sight.
TWN Karunasena, MWS Niranjala
doaj +1 more source
TRH: Pathophysiologic and clinical implications [PDF]
, 1985 Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
Pickardt, C. R., Scriba, Peter Christian
core +1 more source
Thyrotropin Receptor Blocking Antibodies [PDF]
Hormone and Metabolic Research, 2018 Abstract Autoantibodies (Ab) against the thyroid-stimulating hormone receptor (TSHR) are frequently found in autoimmune thyroid disease (AITD). Autoantibodies to the TSHR (anti-TSHR-Ab) may mimic or block the action of TSH or be functionally neutral.
Diana, Tanja +2 more
openaire +3 more sources
Large-Scale Combinatorial Deorphanization of Platynereis Neuropeptide GPCRs
Cell Reports, 2015 Neuropeptides, representing the largest class of neuromodulators, commonly signal by G-protein-coupled receptors (GPCRs). While the neuropeptide repertoire of several metazoans has been characterized, many GPCRs are orphans.
Philipp Bauknecht, Gáspár Jékely
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TOTAL THYROIDECTOMY IN THE MANAGEMENT OF GRAVES' DISEASE [PDF]
Al-Azhar International Medical Journal, 2023 Background; Graves’ disease (GD) is an autoimmune disorder of the thyroid gland in which thyrotropin receptor antibodies (TRAb) stimulate thyroid stimulating hormone receptors (TSH-R), thereby increasing thyroid hormone production and release , Aim and ...
Mohamed Hasan +4 more
doaj +1 more source
Interaction of Human Chorionic Gonadotropin (hCG) and Asialo-hCG with Recombinant Human Thyrotropin Receptor. [PDF]
, 1994 hCG is a putative thyroid stimulator. The present studies were undertaken to examine its interaction and that of its desialylated variant asialo-hCG with recombinant human TSH (hTSH) receptor (hTSHr). To this end, we transfected a human thyroid carcinoma
Mann, K. +4 more
core +1 more source
Sleep Science, 2011 It is possible for normal subjects to fall asleep during daytime wakefulness, and the propensity for daytime sleep varies being high in the mid-afternoon and lower in the early evening 2 or 3 hours before overnight sleep onset.
José Carlos Pereira +1 more
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