Results 51 to 60 of about 10,411 (253)
Age-related thyroid hormone resistance: A friend or foe
Endocrine and Metabolic Science, 2023 Clinical experience shows that older people with hyperthyroidism display fewer signs or symptoms compared to younger people with hyperthyroidism.
Arshag D. Mooradian
doaj +1 more source
Does Thyrotropin Cleave Its Cognate Receptor? [PDF]
Endocrinology, 2004 Abstract A recent report of major pathophysiological significance, and opposed to present concepts, is that TSH (but not MS-1, a hamster monoclonal thyroid-stimulating antibody), cleaves the single-chain TSH receptor (TSHR) on the cell surface into its two-subunit form. We reassessed the issue using two approaches.
Gregorio D, Chazenbalk +3 more
openaire +2 more sources
British Educational Research Journal, EarlyView.Abstract Recruiting and retaining school leaders is a challenge in many systems worldwide. Previous research has identified three distinct ways in which succession planning can be conceptualised and approached: a ‘pipeline’ approach seeks to match supply and demand for the posts that need filling; a ‘pool’ strategy involves proactively identifying and ...
Toby Greany +3 more
wiley +1 more source
eLife, 2019 Serotonin neurons of the dorsal and median raphe nuclei (DR, MR) collectively innervate the entire forebrain and midbrain, modulating diverse physiology and behavior.
Jing Ren +16 more
doaj +1 more source
A tyrosine residue on the TSH receptor stabilizes multimer formation. [PDF]
PLoS ONE, 2010 The thyrotropin stimulating hormone receptor (TSHR) is a G protein coupled receptor (GPCR) with a large ectodomain. The ligand, TSH, acting via this receptor regulates thyroid growth and thyroid hormone production and secretion.
Rauf Latif +3 more
doaj +1 more source
Unconventional Actions of Glycoprotein Hormone Subunits: A Comprehensive Review
Frontiers in Endocrinology, 2021 The glycoprotein hormones (GPH) are heterodimers composed of a common α subunit and a specific β subunit. They act by activating specific leucine-rich repeat G protein-coupled receptors. However, individual subunits have been shown to elicit responses in
Bruno Querat
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 879-887, April 2025.Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot +8 more
wiley +1 more source
Клиническая и экспериментальная тиреоидология, 2006 Introduction: The pathogenesis of Graves’ disease consists in production of stimulating antibodies against thyrotropin receptors (rTHS-AB). In the last decades two different assays for detection of rTHS-AB were introduced in clinical practice: I-st (with
doaj +1 more source
Women with epilepsy: Evidence‐based counseling across the lifespan
Epilepsia, EarlyView.Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn +7 more
wiley +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source